Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking,
satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show …

The “canonical” function of Pax7+ muscle stem cells (satellite cells) during hypertrophic
growth of adult muscle fibers is myonuclear donation via fusion to support increased …

Satellite cells support adult skeletal muscle fiber adaptations to loading in numerous ways.
The fusion of satellite cells, driven by cell‐autonomous and/or extrinsic factors, contributes …

Adult tissue repair and regeneration require stem-progenitor cells that can self-renew and
generate differentiated progeny. Skeletal muscle regenerative capacity relies on muscle …

Skeletal muscle stem cells, or satellite cells (SCs), are essential to regenerate and maintain
muscle. Quiescent SCs reside in an asymmetric niche between the basal lamina and …

Satellite cells, the predominant stem cell population in adult skeletal muscle, are activated in
response to hypertrophic stimuli and give rise to myogenic progenitor cells (MPCs) within …

Background Satellite cells are resident skeletal muscle stem cells responsible for muscle
maintenance and repair. In resting muscle, satellite cells are maintained in a quiescent state …

Satellite cells are required for postnatal development, skeletal muscle regeneration across
the lifespan, and skeletal muscle hypertrophy prior to maturity. Our group has aimed to …

Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Background Maintaining stem cells in physiologically relevant states is necessary to
understand cell and context-specific signalling paradigms and to understand complex …