Esophageal adenocarcinoma incidence is rapidly increasing which may be due to the
growing incidence of Barrett's esophagus (BE) and obesity. The mechanisms linking obesity …

Background Obesity is associated with oesophageal adenocarcinoma, but mechanisms
linking fat and carcinogenesis remain poorly understood. Altered circulating adipocytokines …

Background Oesophageal adenocarcinoma is an exemplar model of an obesity-associated
adenocarcinoma. Altered secretion of adipokines by visceral fat is believed to play a key role …

Background & Aims Central adiposity is a risk factor for Barrett's esophagus (BE). Serum
levels of adiponectin and leptin are deregulated in obese states and are implicated as …

Background & Aims Individuals with Barrett's esophagus (BE) have an increased risk of
developing esophageal adenocarcinoma (EA). Obesity contributes to the development of BE …

The incidence of oesophageal adenocarcinoma has increased dramatically in the
developed world in the last half century. Over approximately the same period there has been …

Obesity increases the risk of developing several cancers including oesophageal
adenocarcinoma (OAC). Obesity is characterised by hyperleptinaemia and …

Background: Obesity is associated with increased risks of Barrett's oesophagus and
oesophageal adenocarcinoma. Alterations in serum leptin and adiponectin, obesity-related …

Background Obesity is an important risk factor for Barrett adenocarcinoma. However, the
role of adiponectin (anti-inflammatory adipokine from adipose tissue) and ghrelin …

Objective: Barrett's oesophagus is associated with abdominal obesity. Adiponectin is a
peptide that is secreted from adipocytes and circulates in three multimeric forms: low …