Circular RNAs as therapeutic agents and targets
LM Holdt, A Kohlmaier, D Teupser - Frontiers in physiology, 2018 - frontiersin.org
It has recently been reported that thousands of covalently linked circular RNAs (circRNAs)
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
The biogenesis, functions, and challenges of circular RNAs
Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
A 360 view of circular RNAs: From biogenesis to functions
JE Wilusz - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
The first circular RNA (circRNA) was identified more than 40 years ago, but it was only
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
Biogenesis and function of circular RNAs in health and in disease
G Haddad, JM Lorenzen - Frontiers in pharmacology, 2019 - frontiersin.org
Circular RNAs (circRNAs) are a class of non-coding RNA that were previously thought to be
insignificant byproducts of splicing errors. However, recent advances in RNA sequencing …
insignificant byproducts of splicing errors. However, recent advances in RNA sequencing …
Circular RNAs: expression, localization, and therapeutic potentials
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …
back-splicing processes. These circular molecules were discovered more than 40 years ago …
Circular RNAs (circRNAs) in health and disease
S Haque, LW Harries - Genes, 2017 - mdpi.com
Splicing events do not always produce a linear transcript. Circular RNAs (circRNAs) are a
class of RNA that are emerging as key new members of the gene regulatory milieu, which …
class of RNA that are emerging as key new members of the gene regulatory milieu, which …
The emerging roles and functions of circular RNAs and their generation
CY Yu, HC Kuo - Journal of biomedical science, 2019 - Springer
Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …
Best practice standards for circular RNA research
AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …
There has been an explosion in the number of circRNA papers in recent years; however, as …
Circular RNAs: isolation, characterization and their potential role in diseases
L Liu, J Wang, R Khanabdali, B Kalionis, X Tai… - RNA biology, 2017 - Taylor & Francis
Circular RNA (circRNA) generated by alternative splicing represents a special class of non-
coding RNA molecule. CircRNAs are abundant in the eukaryotic cell cytoplasm and have a …
coding RNA molecule. CircRNAs are abundant in the eukaryotic cell cytoplasm and have a …