Mechanisms and mediators that drive arthritis pain

E Krustev, D Rioux, JJ McDougall - Current osteoporosis reports, 2015 - Springer
There are over 100 different types of arthritis and each can differ greatly in their aetiology
and pathophysiology; however, one characteristic that is common to all arthritic conditions is …

Mechanisms for joint pain in rheumatoid arthritis (RA): from cytokines to central sensitization

A Zhang, YC Lee - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Pain in rheumatoid arthritis (RA) may be due to different
etiologies, ranging from peripheral inflammation to dysregulation of central nervous system …

[图书][B] Pain in osteoarthritis

DT Felson, HG Schaible - 2009 - books.google.com
An authoritative investigation of the sources and treatment of osteoarthritic joint pain Millions
of people throughout the world suffer from osteoarthritis (OA) a medical condition causing its …

Neuropathic pain in osteoarthritis: a review of pathophysiological mechanisms and implications for treatment

T Dimitroulas, RV Duarte, A Behura, GD Kitas… - Seminars in arthritis and …, 2014 - Elsevier
Objectives Osteoarthritis (OA) is the leading cause of musculoskeletal pain and functional
disability worldwide, affecting a growing number of individuals in the western society …

Neurophysiology of arthritis pain

JJ McDougall, P Linton - Current pain and headache reports, 2012 - Springer
Arthritis pain is a complex phenomenon involving intricate neurophysiological processing at
all levels of the pain pathway. The treatment options available to alleviate joint pain are fairly …

The role of peripheral nociceptive neurons in the pathophysiology of osteoarthritis pain

RE Miller, PB Tran, AM Obeidat, P Raghu… - Current osteoporosis …, 2015 - Springer
Knee osteoarthritis is characterized by progressive damage and remodeling of all tissues in
the knee joint. Pain is the main symptom associated with knee osteoarthritis. Recent clinical …

Peripheral mechanisms contributing to osteoarthritis pain

D Syx, PB Tran, RE Miller, AM Malfait - Current rheumatology reports, 2018 - Springer
Abstract Purpose of Review Osteoarthritis (OA) is the most common form of arthritis and a
major source of pain and disability worldwide. OA-associated pain is usually refractory to …

Mechanisms of osteoarthritic pain. Studies in humans and experimental models

A Eitner, GO Hofmann, HG Schaible - Frontiers in molecular …, 2017 - frontiersin.org
Pain due to osteoarthritis (OA) is one of the most frequent causes of chronic pain. However,
the mechanisms of OA pain are poorly understood. This review addresses the mechanisms …

[HTML][HTML] Peripheral pain mechanisms in osteoarthritis

TL Vincent - Pain, 2020 - journals.lww.com
There is a well-established historical observation that structural joint damage by plain X-ray
correlates poorly with symptomatic disease in osteoarthritis (OA). This is often attributed to …

[PDF][PDF] The genesis of pain in osteoarthritis: inflammation as a mediator of osteoarthritis pain

MJ Wood, RE Miller, AM Malfait - Clinics in geriatric medicine, 2022 - Elsevier
Chronic pain is a substantial personal and societal burden worldwide. Osteoarthritis (OA) is
one of the leading causes of chronic pain and is increasing in prevalence in accordance …