Expression of vascular endothelial growth factor as a prognostic factor in node‐positive squamous cell carcinoma in the thoracic esophagus: Long‐term follow‐up …

Y Ogata, H Fujita, H Yamana, S Sueyoshi… - World journal of …, 2003 - Wiley Online Library
To clarify the clinical significance of the expression of vascular endothelial growth factor
(VEGF) in squamous cell carcinoma in the thoracic esophagus, particularly as a prognostic …

Vascular endothelial growth factor expression predicts outcome and lymph node metastasis in squamous cell carcinoma of the esophagus

CH Shih, S Ozawa, N Ando, M Ueda, M Kitajima - Clinical Cancer Research, 2000 - AACR
Vascular endothelial growth factor (VEGF) expression and tumor microvessel density (MVD)
were examined by immunohistochemical staining in 117 cases of thoracic esophageal …

Histochemical study of vascular endothelial growth factor in squamous cell carcinoma of the esophagus.

N Koide, A Nishio, T Kono, K Yazawa… - Hepato …, 1999 - europepmc.org
Results VEGF expression was observed in 30 of the patients (57.7%). The microvessel
count was significantly higher (p= 0.007), and the apoptotic index was significantly lower (p< …

Vascular endothelial growth factor C (VEGF-C) in esophageal cancer correlates with lymph node metastasis and poor patient prognosis

T Tanaka, H Ishiguro, Y Kuwabara, M Kimura… - Journal of Experimental …, 2010 - Springer
Background The diagnosis of lymph node metastasis in esophageal cancer by the presence
and number of metastatic lymph nodes is an extremely important prognostic factor. In …

VEGF‐C expression in squamous cell carcinoma and adenocarcinoma of the esophagus

C Möbius, J Freire, I Becker, M Feith… - World journal of …, 2007 - Wiley Online Library
Background Vascular endothelial growth factor C (VEGF‐C) is the only factor known to
cause lymphangiogenesis. In esophageal cancer the histologic tumor type and lymph node …

Vascular endothelial growth factor in esophageal cancer

A Kleespies, M Guba, KW Jauch… - Journal of surgical …, 2004 - Wiley Online Library
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis of many solid
malignancies. The influence of angiogenesis and VEGF expression on progression and …

Prognostic value of VEGF expression in primary esophageal squamous cell carcinoma

W Xu, G Yang, L Zhou, Y Xie, L Zhang - Chinese Journal of Cancer …, 2004 - Springer
Objective: To study the expression of vascular endothelial growth factor (VEGF) and
microvessel density (MVD) in esophageal squamous cell carcinoma (ESCC) and clarify the …

Expression of VEGF-C correlates with a poor prognosis based on analysis of prognostic factors in 73 patients with esophageal squamous cell carcinomas

P Liu, W Chen, H Zhu, B Liu, S Song… - Japanese journal of …, 2009 - academic.oup.com
Objective The purpose of this study was to specifically investigate the clinicopathological
role of expression of vascular endothelial growth factor-C (VEGF-C) as well as the …

Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma: association with angiogenesis and tumor progression

K Inoue, Y Ozeki, T Suganuma, Y Sugiura, S Tanaka - Cancer, 1997 - Wiley Online Library
BACKGROUND Angiogenesis is essential for solid tumor growth and metastasis. Vascular
endothelial growth factor (VEGF), a recently identified growth factor with significant …

In oesophageal squamous cell carcinoma vascular endothelial growth factor is associated with p53 mutation, advanced stage and poor prognosis

S Uchida, Y Shimada, G Watanabe, H Tanaka… - British journal of …, 1998 - nature.com
Vascular endothelial growth factor (VEGF) affects malignant tumours by promoting
angiogenesis. The tumour-suppressor gene p53 has been thought to regulate VEGF. We …