Generation of an immune response to a pathogen
PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2004 - Google Patents
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate,
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
Induction of a protective immune response in a mammal by injecting a DNA sequence
PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2001 - Google Patents
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate,
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
Expression of exogenous polynucleotide sequences in a vertebrate
A method for delivering a naked or isolated polynucleotide to the interior of a cell in a
vertebrate, comprising the interstitial introduction of a naked polynucleotide into a tissue of …
vertebrate, comprising the interstitial introduction of a naked polynucleotide into a tissue of …
Methods of delivering a physiologically active polypeptide to a mammal
PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2002 - Google Patents
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate,
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
Expression of exogenous polynucleotide sequences in a vertebrate
(57) ABSTRACT A method for delivering a naked or isolated polynucleotide to the interior of
a cell in a vertebrate, comprising the interstitial introduction of a naked polynucleotide into a …
a cell in a vertebrate, comprising the interstitial introduction of a naked polynucleotide into a …
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2005 - Google Patents
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate,
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …
Induction of a protective immune response in a mammal by injecting a DNA sequence
PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 1996 - Google Patents
57 ABSTRACT A method for delivering an isolated polynucleotide such as DNA or RNA, to
the interior of a cell in a mammal comprising the injection of an isolated polynucleotide into a …
the interior of a cell in a mammal comprising the injection of an isolated polynucleotide into a …
Expression of exogenous polynucleotide sequences in a vertebrate
JA Wolff, DJ Duke, PL Felgner - US Patent 6,706,694, 2004 - Google Patents
The present invention provides a method for delivering a pharmaceutical polypeptide to the
interior of a cardiac cell of a vertebrate in vivo, comprising the step of introducing a …
interior of a cardiac cell of a vertebrate in vivo, comprising the step of introducing a …
Expression of exogenous polynucleotide sequences in a vertebrate
J Wolff, D Duke, P Felgner - US Patent App. 10/360,645, 2003 - Google Patents
The present invention provides a method for delivering a pharmaceutical polypeptide to the
interior of a cardiac cell of a vertebrate in Vivo, comprising the Step of introducing a …
interior of a cardiac cell of a vertebrate in Vivo, comprising the Step of introducing a …
Vectors and method for genetic immunization
JA Williams - US Patent 9,109,012, 2015 - Google Patents
A61K48/005—Medicinal preparations containing genetic material which is inserted into cells
of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …