[HTML][HTML] Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy

Z Le, X Niu, Y Chen, X Ou, G Zhao, Q Liu, W Tu, C Hu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The aim of this study was to investigate the association between the susceptibility of severe
oral mucositis (OM) in Chinese nasopharyngeal carcinoma (NPC) patients treated with …

Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis

DW Yang, TM Wang, JB Zhang, XZ Li, YQ He… - Journal of Translational …, 2020 - Springer
Background Radiation-induced oral mucositis (OM) is one of the most common acute
complications for head and neck cancer. Severe OM is associated with radiation treatment …

Single Nucleotide Polymorphisms as Biomarker Predictors of Oral Mucositis Severity in Head and Neck Cancer Patients Submitted to Combined Radiation Therapy …

R Cavalieri, HF de Oliveira, T Louvain de Souza… - Cancers, 2024 - mdpi.com
Simple Summary Single Nucleotide Polymorphisms (SNPs) are the most common type of
genetic variation found in an individual's DNA sequences. SNPs can occur in both coding …

A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer

E Naderi, APG Crijns, RJHM Steenbakkers… - Journal of translational …, 2021 - Springer
Background Most head and neck cancer (HNC) patients receive radiotherapy (RT) and
develop toxicities. This genome-wide association study (GWAS) was designed to identify …

A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis

LMH Schack, E Naderi, L Fachal, L Dorling… - British journal of …, 2022 - nature.com
Purpose A two-stage genome-wide association study was carried out in head and neck
cancer (HNC) patients aiming to identify genetic variants associated with either specific …

A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

Y Wang, F Xiao, Y Zhao, CX Mao, LL Yu, LY Wang… - Molecular Cancer, 2022 - Springer
Background Genetic variants associated with acute side effects of radiotherapy in
nasopharyngeal carcinoma (NPC) remain largely unknown. Methods We performed a two …

Predictive model and precaution for oral mucositis during chemo-radiotherapy in nasopharyngeal carcinoma patients

PJ Li, KX Li, T Jin, HM Lin, JB Fang, SY Yang… - Frontiers in …, 2020 - frontiersin.org
Purpose To explore risk factors for severe acute oral mucositis of nasopharyngeal
carcinoma (NPC) patients receiving chemo-radiotherapy, build predictive models and …

Polymorphism of promoter region of TNFRSF1A gene (− 610 T> G) as a novel predictive factor for radiotherapy induced oral mucositis in HNC patients

A Brzozowska, T Powrózek, I Homa-Mlak… - Pathology & Oncology …, 2018 - Springer
Every year, about 650 thousand new cases of Head and Neck Cancer (HNC) are diagnosed
globally. Apart from surgery, radiotherapy (RTH), chemotherapy (CHT) or its combination is …

Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: association with genetic polymorphism in DNA DSB repair genes

JH Ren, XF Dai, GL Yan, M Jin, CW Liu… - … journal of radiation …, 2014 - Taylor & Francis
Purpose: The aim of this study was to investigate the association between polymorphic
variants of DNA repair genes with the susceptibility of acute oral mucositis (OM) in …

[HTML][HTML] The impacts of single nucleotide polymorphisms in genes of cell cycle and NF-κB pathways on the efficacy and acute toxicities of radiotherapy in patients with …

C Guo, Y Huang, J Yu, L Liu, X Gong, M Huang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Radiotherapy is one of the primary choices for the treatment of nasopharyngeal carcinoma
(NPC) and may result in severe radiotoxicities on normal tissues. Single nucleotide …