Minocycline has anti-inflammatory, antioxidant, and anti-apoptotic properties that explain the
renewed interest in its use as an adjunctive treatment for psychiatric and neurological …

Background and purpose Minocycline is a broad‐spectrum antibiotic, effective as a chronic
treatment for recurrent bacterial infections. Beyond its antibiotic action, minocycline also has …

Pharmacological interventions to treat psychiatric illness have previously focused on
modifying dysfunctional neurotransmitter systems to improve symptoms. However, imperfect …

Objectives: This meta-analysis of randomized controlled trials (RCTs) examined the efficacy
and safety of minocycline for three major mental disorders: schizophrenia, bipolar disorder …

Minocycline, an antibiotic of the tetracycline family, has been shown to display
neurorestorative or neuroprotective properties in various models of neurodegenerative …

Background Minocycline has been identified as a potential novel treatment for depression.
The objective of the current review is to determine the overall antidepressant efficacy and …

ObjectiveOur aim was to perform an updated systematic review and meta-analysis on the
efficacy and safety of adjunctive minocycline as a treatment of schizophrenia. MethodsWe …

Objective This study aimed to perform a comprehensive meta‐analysis of minocycline
augmentation therapy in patients with schizophrenia receiving antipsychotic agents …

Background: Current antipsychotics have only a limited effect on 2 core aspects of
schizophrenia: negative symptoms and cognitive deficits. Minocycline is a second …

Background Depression is one of the leading causes of disability worldwide. A high
proportion of patients do not respond to standard drug treatments. Recent evidence has …