Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium
transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in …

ABSTRACT Q fever, a worldwide zoonosis caused by Coxiella burnetii, has many
manifestations in humans. Endocarditis is the most serious complication of Q fever. Animal …

Coxiella burnetii, the causative agent of Q fever, has evolved a wealth of mechanisms in
order to persist within hosts. Two tissues, namely adipose tissue and placenta, are …

A 67 K outer membrane protein (OMP) isolated from phase I Coxiella burnetii QiYi strain was
purified with monoclonal antibodies (MoAb) coupled to CNBr-Sepharose 4B. Chemical …

Coxiella burnetii is a Gram-negative intracellular bacterium and is the causative agent of the
zoonotic disease Q fever. Several rodent and non-human primate models of virulent phase I …

Coxiella burnetii has two phase variants: highly virulent phase I and avirulent phase II. To
examine the differences between the two phase variants in interaction with host response to …

Q fever is an acute and self-limited febrile illness caused by the obligate intracellular
bacterium Coxiella burnetii. While phase I cellular Q fever vaccines are efficacious in …

Background Coxiella burnetii is the causative agent of the zoonotic disease Q fever. As it is
an intracellular pathogen, infection by C. burnetii requires adaptation to its eukaryotic host …

Coxiella burnetii causes acute Q fever in humans and occasional chronic infections that
typically manifest as endocarditis or hepatitis. Isolates associated with acute disease were …

Q fever is caused by Coxiella burnetii, a bacterium that survives in monocytes/macrophages
by resisting their natural microbicidal activity. Because the link between bacterial killing and …