Role of B cells in host defense against primary Coxiella burnetii infection

L Schoenlaub, A Elliott, D Freches… - Infection and …, 2015 - Am Soc Microbiol
Despite Coxiella burnetii being an obligate intracellular bacterial pathogen, our recent study
demonstrated that B cells play a critical role in vaccine-induced immunity to C. burnetii …

Natural history and pathophysiology of Q fever

D Raoult, TJ Marrie, JL Mege - The Lancet infectious diseases, 2005 - thelancet.com
Q fever is a zoonosis caused by Coxiella burnetii. Infection with C burnetii can be acute or
chronic, and exhibits a wide spectrum of clinical manifestations. The extreme infectivity of the …

Long-term persistence after acute Q fever of non-infective Coxiella burnetii cell components, including antigens

OA Sukocheva, BP Marmion, PA Storm… - … Journal of Medicine, 2010 - academic.oup.com
Background: Previous studies of inciting factors for a prolonged post-infection fatigue
syndrome after Q fever (variously termed QFS or Q fever associated CFS/ME in the …

Developmental biology of Coxiella burnetii

RA Heinzen, T Hackstadt, JE Samuel - Trends in microbiology, 1999 - cell.com
The obligate intracellular bacterial agent of human Q fever, Coxiella burnetii, has a
remarkable ability to persist in the extracellular environment. It replicates only when …

Characterization of a phase I Coxiella burnetii chloroform-methanol residue vaccine that induces active immunity against Q fever in C57BL/10 ScN mice

JC Williams, TA Damrow, DM Waag… - Infection and …, 1986 - Am Soc Microbiol
The effect of phase I Coxiella burnetii chloroform-methanol residue vaccine (CMRV) on the
response of murine splenic lymphocytes to mitogenic and antigenic stimuli was evaluated in …

Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro

TD Fernandes, LD Cunha, JM Ribeiro… - Infection and …, 2016 - Am Soc Microbiol
Coxiella burnetii is a Gram-negative bacterium that causes Q fever in humans. Q fever is an
atypical pneumonia transmitted through inhalation of contaminated aerosols. In mammalian …

Roles of toll-like receptor 2 (TLR2), TLR4, and MyD88 during pulmonary Coxiella burnetii infection

AG Ramstead, A Robison, A Blackwell… - Infection and …, 2016 - Am Soc Microbiol
Coxiella burnetii, the causative agent of Q fever, is an obligate intracellular, primarily
pulmonary, bacterial pathogen. Although much is known about adaptive immune responses …

Coxiella burnetii Exhibits Morphological Change and Delays Phagolysosomal Fusion after Internalization by J774A.1 Cells

D Howe, LP Mallavia - Infection and immunity, 2000 - Am Soc Microbiol
Coxiella burnetii, the etiological agent of Q fever, is an obligate intracellular bacterium
proliferating within the harsh environment of the phagolysosome. Mechanisms controlling …

Limited humoral and cellular responses to Q fever vaccination in older adults with risk factors for chronic Q fever

T Schoffelen, T Herremans, T Sprong… - Journal of Infection, 2013 - Elsevier
Summary Objectives In the Netherlands, people at risk for chronic Q fever were vaccinated
against Coxiella burnetii with the inactivated whole cell vaccine Q-vax®. We aimed to …

From Q fever to Coxiella burnetii infection: a paradigm change

C Eldin, C Mélenotte, O Mediannikov… - Clinical microbiology …, 2017 - Am Soc Microbiol
Coxiella burnetii is the agent of Q fever, or “query fever,” a zoonosis first described in
Australia in 1937. Since this first description, knowledge about this pathogen and its …