Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases
MR de Vries, MM Ewing, RCM de Jong… - Journal of Internal …, 2021 - Wiley Online Library
Background Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated
molecular pattern. Previous data have shown that natural IgM anti‐PC protects against …
molecular pattern. Previous data have shown that natural IgM anti‐PC protects against …
Long-term prognostic value of IgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease
A Imhof, W Koenig, A Jaensch, U Mons, H Brenner… - Atherosclerosis, 2015 - Elsevier
Abstract Background Low concentrations of IgM-phosphorylcholine autoantibodies (IgM-anti-
PC) have been shown to be associated with increased risk of incident cardiovascular …
PC) have been shown to be associated with increased risk of incident cardiovascular …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men
B Gigante, K Leander, M Vikström, D Baldassarre… - Atherosclerosis, 2014 - Elsevier
Abstract Objective Low levels of IgM anti-phosphorylcholine (anti-PC) increase the risk of
cardiovascular events (CVE). Here we investigate the association of low anti-PC with the …
cardiovascular events (CVE). Here we investigate the association of low anti-PC with the …
Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial
BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
Atherogenesis is a complex inflammatory process stemming from the accumulation and
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
Antibodies against phosphorylcholine among New Guineans compared to Swedes: an aspect of the hygiene/missing old friends hypothesis
J Frostegård, WJ Tao, L Råstam… - Immunological …, 2017 - Taylor & Francis
Background: We here study antibodies against phosphorylcholine (anti-PC) which we
reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and …
reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and …
[图书][B] Natural antibodies against phosphorylcholine as potential protective factors in atherosclerosis, cardiovascular disease and systemic lupus erythematosus
J Su - 2009 - search.proquest.com
Natural antibodies against phosphorylcholine as potential protective factors in atherosclerosis,
cardiovascular disease and sy Page 1 Institutionen för Medicin, Enheten för Akutmedicin …
cardiovascular disease and sy Page 1 Institutionen för Medicin, Enheten för Akutmedicin …
Antibodies against phosphorylcholine in hospitalized versus non-hospitalized obese subjects
Obesity associates with reduced life expectancy, type 2 diabetes, hypertension and
cardiovascular disease, and is characterized by chronic inflammation. Phosphorylcholine …
cardiovascular disease, and is characterized by chronic inflammation. Phosphorylcholine …
[HTML][HTML] IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with …
R Fiskesund, J Su, I Bulatovic, M Vikström… - Results in …, 2012 - Elsevier
Background We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease
CA Gleissner, C Erbel, J Haeussler… - Clinical Research in …, 2015 - Springer
Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …