Protective vascular and myocardial effects of adiponectin

BJ Goldstein, RG Scalia, XL Ma - Nature clinical practice Cardiovascular …, 2009 - nature.com
Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective
effects in the vasculature and myocardium. In obesity and insulin-resistant states …

Adiponectin and cardiovascular risk. From pathophysiology to clinic: focus on children and adolescents

A Orlando, E Nava, M Giussani, S Genovesi - International journal of …, 2019 - mdpi.com
Adiponectin (Ad) is a cytokine produced by adipocytes that acts on specific receptors of
several tissues through autocrine, paracrine, and endocrine signaling mechanisms. Ad is …

Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-α expression

PA Kern, GB Di Gregorio, T Lu, N Rassouli… - Diabetes, 2003 - Am Diabetes Assoc
Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin resistance of
obesity and lipodystrophy. To better understand the regulation of adiponectin expression …

Adiponectin as a routine clinical biomarker

K Kishida, T Funahashi, I Shimomura - Best practice & research Clinical …, 2014 - Elsevier
Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the
peripheral blood. However, circulating adiponectin level is inversely related with body …

Adiponectin as a biomarker of the metabolic syndrome

M Ryo, T Nakamura, S Kihara, M Kumada… - Circulation …, 2004 - jstage.jst.go.jp
Background The metabolic syndrome, a cluster of abdominal obesity, dyslipidemia,
hypertension and hyperglycemia, is a common basis for atherosclerotic vascular diseases in …

Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?

EZ Fisman, A Tenenbaum - Cardiovascular diabetology, 2014 - Springer
Adiponectin is the most abundant peptide secreted by adipocytes, being a key component in
the interrelationship between adiposity, insulin resistance and inflammation. Central obesity …

Plasma adiponectin in overweight, nondiabetic individuals with or without insulin resistance

BI Shand, RS Scott, PA Elder… - Diabetes, Obesity and …, 2003 - Wiley Online Library
Aim: Adiponectin is a protein produced exclusively by adipocytes with putative insulin‐
sensitizing and anti‐atherogenic properties. This cross‐sectional study investigated the …

Obesity, adiponectin and vascular inflammatory disease

N Ouchi, S Kihara, T Funahashi… - Current opinion in …, 2003 - journals.lww.com
Obesity, adiponectin and vascular inflammatory disease : Current Opinion in Lipidology
Obesity, adiponectin and vascular inflammatory disease : Current Opinion in Lipidology Log in …

Adiponectin and its isoforms in pathophysiology

M van Andel, AC Heijboer, ML Drent - Advances in clinical chemistry, 2018 - Elsevier
Adiponectin circulates in blood in multiple isoforms. High molecular weight (HMW)
adiponectin is thought to be most biologically active and promotes glucose uptake, insulin …

Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin

WS Yang, WJ Lee, T Funahashi… - The Journal of …, 2001 - academic.oup.com
Adiponectin, an adipose tissue-specific plasma protein, was recently revealed to have anti-
inflammatory effects on the cellular components of vascular wall. Its plasma levels were …