[HTML][HTML] Different properties of ACPA and IgM-RF derived from a large dataset: further evidence of two distinct autoantibody systems

J Ursum, WH Bos, RJ van de Stadt… - Arthritis research & …, 2009 - Springer
Introduction The aim of this study was to examine seroconversion and the relationship with
age and inflammation of autoantibodies in a large group of patients attending an outpatient …

[HTML][HTML] Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

M Brink, M Hansson, L Mathsson-Alm… - Arthritis research & …, 2016 - Springer
Background The presence of rheumatoid factor (RF), anti-carbamylated protein antibodies
(anti-CarP) and antibodies against citrullinated protein and peptides (ACPA) precedes the …

[HTML][HTML] The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

DM Boeters, L Mangnus, S Ajeganova… - Arthritis research & …, 2017 - Springer
Background Rheumatoid arthritis (RA) consists of two syndromes, one autoantibody-positive
and one autoantibody-negative. Existing data on the relation between age of onset and …

[HTML][HTML] Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides

M Hansson, L Mathsson, T Schlederer… - Arthritis research & …, 2012 - Springer
Introduction Autoantibodies directed against citrullinated proteins/peptides (ACPAs) are
highly specific and predictive for the development of rheumatoid arthritis (RA). Different …

Autoantibodies in prediction of the development of rheumatoid arthritis among healthy relatives of patients with the disease

C Ramos‐Remus, JD Castillo‐Ortiz… - Arthritis & …, 2015 - Wiley Online Library
Objective Although blood bank–based studies have shown that rheumatoid arthritis (RA)–
related autoantibodies are present before the onset of RA, information on their positive …

Do autoantibody-responses mature between presentation with arthralgia suspicious for progression to rheumatoid arthritis and development of clinically apparent …

F Wouters, E Niemantsverdriet, N Salioska… - Annals of the …, 2021 - ard.bmj.com
Figure 1 Changes in autoantibody response over time:(A) percentage of patients with
seroconversion to positive in patients negative for all autoantibodies at baseline,(B) …

[HTML][HTML] Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

EC de Moel, VFAM Derksen, G Stoeken… - Arthritis research & …, 2018 - Springer
Background The autoantibody profile of seropositive rheumatoid arthritis (RA) is very diverse
and consists of various isotypes and antibodies to multiple post-translational modifications. It …

[HTML][HTML] ACPA fine-specificity profiles in early rheumatoid arthritis patients do not correlate with clinical features at baseline or with disease progression

JJBC van Beers, A Willemze, JJ Jansen… - Arthritis research & …, 2013 - Springer
Introduction Autoantibodies against citrullinated peptides/proteins (ACPA) are found in
approximately 75% of the sera of patients with rheumatoid arthritis (RA). The RA-specific …

[HTML][HTML] Differences in synovial fluid cytokine levels but not in synovial tissue cell infiltrate between anti-citrullinated peptide/protein antibody-positive and–negative …

JA Gómez-Puerta, R Celis, MV Hernández… - Arthritis research & …, 2013 - Springer
Introduction Comparative data on synovial cell infiltrate and cytokine levels in anti
citrullinated peptide/protein antibody (ACPA)-positive and ACPA negative rheumatoid …

Timing of elevations of autoantibody isotypes prior to diagnosis of rheumatoid arthritis

LB Kelmenson, BD Wagner, BK McNair… - Arthritis & …, 2020 - Wiley Online Library
Objective To evaluate patterns of elevations of isotypes of rheumatoid factor (RF) and anti–
citrullinated protein antibodies (ACPAs) pre–rheumatoid arthritis (RA) diagnosis and post …