Excitation-contraction coupling involves the faithful conversion of electrical stimuli to
mechanical shortening in striated muscle cells, enabled by the ubiquitous second …

Ryanodine receptors (RyRs) are located in the sarcoplasmic/endoplasmic reticulum
membrane and are responsible for the release of Ca2+ from intracellular stores during …

Ryanodine receptors (RyRs) are high conductance intracellular cation channels that release
calcium ions from stores such as the endoplasmic reticulum and sarcoplasmic reticulum …

Regulation of intracellular calcium (Ca 2+) is critical in all cell types. The ryanodine receptor
(RyR), an intracellular Ca 2+ release channel located on the sarco/endoplasmic reticulum …

This Review provides an update on ryanodine receptors (RyRs) and their role in human
diseases of heart, muscle, and brain. Calcium (Ca2+) is a requisite second messenger in all …

Ryanodine receptor calcium release channels (RyRs) play central roles in controlling
intracellular calcium concentrations in excitable and non-excitable cells. RyRs are located in …

The ryanodine receptor (RyR) is a high-conductance Ca2+ channel of the sarcoplasmic
reticulum in muscle and of the endoplasmic reticulum in other cells. In striated muscle fibers …

Ryanodine receptors (RyRs) are huge ion channels that are responsible for the release of
Ca 2+ from the sarco/endoplasmic reticulum. RyRs form homotetramers with a mushroom …

The ryanodine receptor (RyR) calcium release channel is an essential intracellular ion
channel that is central to Ca2+ signaling and contraction in the heart and skeletal muscle …

Large-conductance Ca2+ release channels known as ryanodine receptors (RyRs) mediate
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …