Helicobacter pylori (H. pylori) infection is the leading cause of gastric cancer worldwide.
Infection with this bacterium causes a chronic active immune response that persists for the …

Background: The host genetic factors that determine the clinical outcomes of Helicobacter
pylori‐infected individuals remain unclear. Aim: To elucidate the risks of host interleukin‐1 …

Helicobacter pylori infects half of the world's population, and is associated with
asymptomatic gastritis and also with more serious conditions such as peptic ulcer disease …

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells
activated by chronic Helicobacter pylori (H. pylori) infection. Polymorphisms of these …

OBJECTIVES The association between interleukin-1 polymorphisms, H. pylori and
increased gastric cancer risk remains controversial. AIMS To compare the prevalence of …

Host genetic factors have recently been focused on as the reasons for the divergent clinical
outcomes by Helicobacter pylori (H. pylori) infection. Interleukin-1 beta (IL-B) is one of the …

OBJECTIVES Host genetic factors, including the IL1 gene cluster, play a key role in
determining the long-term outcome of Helicobacter pylori infection. The aim of the study was …

Abstract Interleukin 2 (IL-2) is a pro-inflammatory cytokine that is mainly synthesized by
immunoregulatory T helper cells and which plays an important role in antitumor immunity …

Background:: Polymorphisms in the interleukin 1β gene (IL-1B-31T/C and IL-1B-511C/T
single nucleotide changes) and in the interleukin 1 receptor anatagonist gene (IL-1RN2 …

Helicobacter pylori is one of the major risk factors involved in the development ofgastritis
and gastric cancer (GC). H. pylori infection leads to increased production of pro …