Although progress has been made identifying neural mechanisms underlying ethanol's
primary reinforcing effects, few studies have examined the mechanisms mediating ethanol …

There is a strong interest in harnessing the genetic manipulations that are possible in mice
to investigate the functional neural mechanisms modulating the associative processes that …

Although progress has been made identifying the neural areas underlying the primary
reinforcing effects of ethanol, few studies have examined the neural areas mediating ethanol …

The neurobiological processes by which ethanol seeking and consumption are established
and maintained are thought to involve areas of the brain that mediate motivated behavior …

This study was conducted to assess the involvement of N-methyl-d-aspartate (NMDA) and γ-
aminobutyric acid (GABA) receptor systems, located in specific limbic brain regions, in the …

Alcoholism is a chronic recurring brain disorder causing the afflicted a multitude of social
and health problems and enormous costs to society. The psychosocial and pharmacological …

Ethanol-induced elevations of accumbal dopamine levels have been linked to the
reinforcing properties of the drug. However, it has not yet been demonstrated where the …

The purpose of this study was to assess the role of endogenous dopamine and glutamate
systems within the nucleus accumbens in modulating responses for oral ethanol …

Using a well-established model of ethanol dependence and relapse, this study examined
adaptations in glutamatergic transmission in the nucleus accumbens (NAc) and their role in …

Regulation of NMDAreceptor‐mediated synaptic transmission onto accumbal medium spiny
neurons (MSN) may constitute an important site in drug reward and reinforcement in …