Getting to the heart of asthma: Can “β blockers” be useful to treat asthma?

RA Bond, D Spina, S Parra, CP Page - Pharmacology & therapeutics, 2007 - Elsevier
β2-adrenoceptor agonists are the mainstay for the acute symptomatic treatment of asthma
and provide effective bronchoprotection to a wide range of bronchoconstrictor agents …

Beta-blockers: friend or foe in asthma?

B Arboe, CS Ulrik - International journal of general medicine, 2013 - Taylor & Francis
Background and aim Recently, β-blockers have been suggested as a potential maintenance
treatment option for asthma. The aim of this review is to provide an overview of the current …

Beta-blockers in asthma: myth and reality

A Tiotiu, P Novakova, K Kowal… - Expert review of …, 2019 - Taylor & Francis
Introduction: Patients with asthma often have important co-morbidities which reduce the
likelihood of gaining optimal asthma control. Beta2-blockers are commonly prescribed for …

What is New with the β2-Agonists: Issues in the Management of Asthma

HW Kelly - Annals of Pharmacotherapy, 2005 - journals.sagepub.com
OBJECTIVE: To review the more recent literature addressing the issue of whether β2-
agonists can worsen asthma and/or increase the risk of severe exacerbations and death …

β-Agonists and asthma: too much of a good thing?

SA Shore, JM Drazen - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
In an unusual paradox, asthmatics who are chronically treated with bronchodilating β-
agonists sometimes experience a worsening of their condition. A new study describes one …

Long-acting β2-adrenoceptor agonists: a smart choice for asthma?

BJ Lipworth - Trends in pharmacological sciences, 2007 - cell.com
An endogenous defect in β 2-adrenoceptors that results in impaired relaxation of airway
smooth muscle was originally proposed as a putative underlying cause of the asthmatic …

[HTML][HTML] Past, present and future—β2-adrenoceptor agonists in asthma management

MR Sears, J Lötvall - Respiratory medicine, 2005 - Elsevier
The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …

The beta-agonist controversy

DR Taylor, MR Sears, DW Cockcroft - Medical Clinics, 1996 - medical.theclinics.com
BACKGROUND Despite widespread use of adrenergic agents in the management of
asthma for many decades, doubts have emerged concerning the safety and efficacy of long …

The β-agonist saga and its clinical relevance: on and on it goes

DR Taylor - American journal of respiratory and critical care …, 2009 - atsjournals.org
The decision by the Food and Drug Administration to issue a “black box” warning for long-
acting β-agonists has been followed by a series of pharmacoepidemiological studies …

Excess mortality in patients with asthma on long-acting β2-agonists

J Hasford, JC Virchow - European Respiratory Journal, 2006 - Eur Respiratory Soc
Asthma ranks among the most common of chronic diseases in the Western world. Although
modern therapy has improved patient care, asthma still affects 5–10% of the population and …