Local glutamate receptor antagonism in the rat prefrontal cortex disrupts response inhibition in a visuospatial attentional task

ER Murphy, JW Dalley, TW Robbins - Psychopharmacology, 2005 - Springer
Rationale Converging evidence implicates discrete areas of the rat prefrontal cortex in the
modulation of different aspects of attention and executive control. Furthermore, the …

Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex

ER Murphy, ABP Fernando, GP Urcelay… - …, 2012 - Springer
Rationale Previous work has demonstrated a profound effect of N-methyl-d-aspartic acid
receptor (NMDAR) antagonism in the infralimbic cortex (IL) to selectively elevate impulsive …

The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex

C Mirjana, M Baviera, RW Invernizzi… - …, 2004 - nature.com
We investigated whether 5-HT 2A receptors contribute to the control of attentional
performance by glutamate NMDA receptor mechanisms in the medial prefrontal cortex …

Attention deficit induced by blockade of N-methyl D-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response …

L Pozzi, M Baviera, G Sacchetti, E Calcagno… - Neuroscience, 2011 - Elsevier
The hypothesis that attention deficits induced by the hypofunction of N-methyl d-aspartate
(NMDA) receptors in the prefrontal cortex (PFC) might be associated with increased …

Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade

E Calcagno, M Carli, M Baviera… - Journal of …, 2009 - Wiley Online Library
Blockade of NMDA receptors by intracortical infusion of 3‐(R)‐2‐carboxypiperazin‐4‐propyl‐
1‐phosphonic acid (CPP) increases glutamate (GLU) and serotonin (5‐HT) release in the …

The 5‐HT2A receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC

I Ceglia, M Carli, M Baviera, G Renoldi… - Journal of …, 2004 - Wiley Online Library
We recently found that intracortical injection of the selective and competitive N‐methyl‐d‐
aspartate (NMDA) receptor antagonist 3‐(R)‐2‐carboxypiperazin‐4‐propyl‐1‐phosphonic …

Double dissociation of serotonergic and dopaminergic mechanisms on attentional performance using a rodent five-choice reaction time task

F Passetti, JW Dalley, TW Robbins - Psychopharmacology, 2003 - Springer
Rationale. Converging evidence suggests that dopaminergic and serotonergic mechanisms
affect distinct aspects of cognitive performance. Experiments using the rodent five-choice …

Haloperidol and clozapine have dissociable effects in a model of attentional performance deficits induced by blockade of NMDA receptors in the mPFC

M Baviera, RW Invernizzi, M Carli - Psychopharmacology, 2008 - Springer
Rationale Cognitive impairment in schizophrenia is particularly evident in the domains of
attention and executive functions. Atypical antipsychotics are somewhat more effective than …

Investigating glutamatergic mechanism in attention and impulse control using rats in a modified 5-choice serial reaction time task

A Benn, ESJ Robinson - PloS one, 2014 - journals.plos.org
The 5-choice serial reaction time task (5CSRTT) has been widely used to study attention
and impulse control in rodents. In order to mimic cognitive impairments in psychiatry, one …

Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex

S Granon, F Passetti, KL Thomas… - Journal of …, 2000 - Soc Neuroscience
The role in spatial divided and sustained attention of D1 and D2-like dopamine (DA)
receptors in the rat prelimbic medial prefrontal cortex (mPFC) was investigated in a five …