BACKGROUND Patients with difficult asthma suffer chronic moderate to severe persistent
asthma symptoms despite high doses of inhaled and oral corticosteroid therapy. These …

Objective: Exhaled nitric oxide (eNO) has been used as a surrogate of airway inflammation
in mild asthma. However, whether eNO levels reflect disease activity in symptomatic …

There has been intense research into the role nitric oxide (NO) plays in physiological and
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …

Study objective To examine whether atopy influencesexhaled nitric oxide (NO) levels in
adults with establishedasthma. Setting Specialist respiratory unit in auniversity teaching …

Controlled studies have shown that monitoring of the exhaled nitric oxide fraction (F eNO)
improves asthma management. However, the studies seldom consider the full range of …

An increased concentration of nitric oxide (NO) in the exhaled air of asthmatic patients may
reflect inflammation of the airways, and exhaled NO may, therefore, be useful in monitoring …

Nitric oxide (NO) is synthesized from the amino acid arginine by enzymes called nitric oxide
synthases. NO has an important physiologic role in the regulation of vascular tone, response …

Background: Asthma guidelines emphasize maintaining disease control. However, objective
measures of asthma disease control are lacking. Objective: We sought to examine the …

Bronchial asthma is an airway disorder associated with bronchial hyperresponsiveness,
variable airflow obstruction and elevated levels of nitric oxide (NO) in exhaled air. The …

The fraction of exhaled nitric oxide (FeNO) is elevated in asthmatics compared to normal
subjects. Many studies have demonstrated that FeNO correlates with other markers of …