Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled …
RG Stirling, SA Kharitonov, D Campbell, DS Robinson… - Thorax, 1998 - thorax.bmj.com
BACKGROUND Patients with difficult asthma suffer chronic moderate to severe persistent
asthma symptoms despite high doses of inhaled and oral corticosteroid therapy. These …
asthma symptoms despite high doses of inhaled and oral corticosteroid therapy. These …
Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid‐treated adult asthmatic patients
Objective: Exhaled nitric oxide (eNO) has been used as a surrogate of airway inflammation
in mild asthma. However, whether eNO levels reflect disease activity in symptomatic …
in mild asthma. However, whether eNO levels reflect disease activity in symptomatic …
Clinical aspects of exhaled nitric oxide
SA Kharitonov, PJ Barnes - European Respiratory Journal, 2000 - Wiley Online Library
There has been intense research into the role nitric oxide (NO) plays in physiological and
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …
Atopy influences exhaled nitric oxide levels in adult asthmatics
LP Ho, FT Wood, A Robson, JA Innes, AP Greening - Chest, 2000 - Elsevier
Study objective To examine whether atopy influencesexhaled nitric oxide (NO) levels in
adults with establishedasthma. Setting Specialist respiratory unit in auniversity teaching …
adults with establishedasthma. Setting Specialist respiratory unit in auniversity teaching …
Exhaled nitric oxide and asthma control: a longitudinal study in unselected patients
A Michils, S Baldassarre… - European respiratory …, 2008 - Eur Respiratory Soc
Controlled studies have shown that monitoring of the exhaled nitric oxide fraction (F eNO)
improves asthma management. However, the studies seldom consider the full range of …
improves asthma management. However, the studies seldom consider the full range of …
Changes in the dose of inhaled steroid affect exhaled nitric oxide levels in asthmatic patients
SA Kharitonov, DH Yates, KF Chung… - European respiratory …, 1996 - Eur Respiratory Soc
An increased concentration of nitric oxide (NO) in the exhaled air of asthmatic patients may
reflect inflammation of the airways, and exhaled NO may, therefore, be useful in monitoring …
reflect inflammation of the airways, and exhaled NO may, therefore, be useful in monitoring …
Nitric oxide and asthma: a review
K Ashutosh - Current opinion in pulmonary medicine, 2000 - journals.lww.com
Nitric oxide (NO) is synthesized from the amino acid arginine by enzymes called nitric oxide
synthases. NO has an important physiologic role in the regulation of vascular tone, response …
synthases. NO has an important physiologic role in the regulation of vascular tone, response …
Exhaled nitric oxide levels correlate with measures of disease control in asthma
JM Sippel, WE Holden, SA Tilles, M O'Hollaren… - Journal of Allergy and …, 2000 - Elsevier
Background: Asthma guidelines emphasize maintaining disease control. However, objective
measures of asthma disease control are lacking. Objective: We sought to examine the …
measures of asthma disease control are lacking. Objective: We sought to examine the …
Exhaled nitric oxide; relationship to clinicophysiological markers of asthma severity
MK Al-Ali, C Eames, PH Howarth - Respiratory medicine, 1998 - Elsevier
Bronchial asthma is an airway disorder associated with bronchial hyperresponsiveness,
variable airflow obstruction and elevated levels of nitric oxide (NO) in exhaled air. The …
variable airflow obstruction and elevated levels of nitric oxide (NO) in exhaled air. The …
Exhaled nitric oxide predicts asthma exacerbation
MS Harkins, KL Fiato, GK Iwamoto - Journal of Asthma, 2004 - Taylor & Francis
The fraction of exhaled nitric oxide (FeNO) is elevated in asthmatics compared to normal
subjects. Many studies have demonstrated that FeNO correlates with other markers of …
subjects. Many studies have demonstrated that FeNO correlates with other markers of …