Background Diet quality is a risk factor for chronic disease and mortality. Differential DNA
methylation across the epigenome has been associated with chronic disease risk. Whether …

Waist circumference (WC) and waist-to-hip ratio (WHR) are surrogate measures of central
adiposity that are associated with adverse cardiovascular events, type 2 diabetes and …

Epigenetics links perinatal influences with later obesity. We identifed differentially
methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity …

Abstract Background/Objective: Recently, several studies have reported that DNA
methylation changes in tissue are reflected in blood, sparking interest in the potential use of …

Increased adiposity is a hallmark of obesity and overweight, which affect 2.2 billion people
world-wide. Understanding the genetic and molecular mechanisms that underlie obesity …

Recent genome‐wide association studies (GWAS) have identified multiple novel loci
associated with obesity in Europeans but results in other ethnicities are less convincing …

Genome-wide association studies (GWASs) primarily performed in European-ancestry (EA)
populations have identified numerous loci associated with body mass index (BMI). However …

Background Metabolically healthy obesity (MHO) is a considerably controversial concept as
it is considered a transitory condition towards the development of different pathologies (type …

Central obesity is a leading health concern with a great burden carried by ethnic minority
populations, especially Hispanics/Latinos. Genetic factors contribute to the obesity burden …

Background One of the major challenges in obesity treatment is to explain the high
variability in the individual's response to specific dietary and physical activity interventions …