Hemorrhagic stroke is a devastating disease with high morbidity and mortality. There is still a
lack of effective therapeutic approach. The recent studies have shown that the innate …

Hemorrhagic stroke is a devastating clinical event with no effective medical treatment.
Neuroinflammation, which follows a hemorrhagic stroke, is an important element that …

Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke; there is still a lack of
effective treatment. Microglia are a major component of the innate immune system, and they …

Ischemic stroke is one of the main causes of death and disablement globally. The NLR
family pyrin domain containing 3 (NLRP3) inflammasome is established as a sensor of …

The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …

Stroke is one of the major devastating diseases with no effective medical therapeutics.
Because of the high rate of disability and mortality among stroke patients, new treatments …

Inflammation is a devastating pathophysiological process during stroke, a devastating
disease that is the second most common cause of death worldwide. Activation of the NOD …

Background Recently, several studies have demonstrated that the NLRP3 inflammasome
participates in detecting cellular damage and mediating inflammatory responses to aseptic …

Inflammasome pattern recognition receptors, which belong to the family of multi-meric
proteins, play an important role in innate immunity, including NLRPs, NLRC, and NAIP …

Millions of patients are suffering from ischemic stroke, it is urgent to figure out the
pathogenesis of cerebral ischemia–reperfusion (I/R) injury in order to find an effective cure …