Emerging therapeutics for Alzheimer's disease

ERLC Vardy, I Hussain, NM Hooper - Expert Review of …, 2006 - Taylor & Francis
Alzheimer's disease (AD) is the most common form of dementia, with prevalence and the
accompanying socioeconomic impact set to increase over the coming decades. Currently …

Amyloid beta modulators and neuroprotection in Alzheimer's disease: a critical appraisal

CS Kuruva, PH Reddy - Drug discovery today, 2017 - Elsevier
Highlights•Multiple cellular changes have been identified as being involved in AD
pathogenesis.•Studies concluded that abnormal APP processing causes Aβ-induced …

[HTML][HTML] New treatment strategies for Alzheimer's disease: is there a hope?

I Aprahamian, F Stella, OV Forlenza - Indian Journal of Medical …, 2013 - journals.lww.com
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, and
corresponds to the most common cause of dementia worldwide. Although not fully …

Reducing Aβ load and tau phosphorylation: Emerging perspective for treating Alzheimer's disease

J Kalra, A Khan - European journal of pharmacology, 2015 - Elsevier
Alzheimer's disease (AD) is a complex, progressive neurological disorder affecting elderly
population of above 65 years of age, characterized by failure of memory, loss of acquired …

Recent trends in treatment strategies for Alzheimer's disease and the challenges: A topical advancement

N Liu, X Liang, Y Chen, L Xie - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's Disease (AD) is an irreversible and progressive neurological disease that has
affected at least 50 million people around the globe. Considering the severity of the disease …

An effective treatment for Alzheimer's disease must consider both amyloid and tau

CJ Lansdall - Bioscience Horizons, 2014 - academic.oup.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder resulting in cognitive
impairment, loss of executive functions and progressive dementia. AD is the most common …

Update on Alzheimer's disease therapy and prevention strategies

WV Graham, A Bonito-Oliva… - Annual review of …, 2017 - annualreviews.org
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …

Update on the pharmacological treatment of Alzheimer's disease

F Massoud, S Gauthier - Current neuropharmacology, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Worldwide
prevalence of the disease is estimated at more than 24 million cases. With aging of …

Current and future therapy in Alzheimer's disease

RJ Van Marum - Fundamental & clinical pharmacology, 2008 - Wiley Online Library
Dementia is increasingly being recognized as one of the most important medical problems
in the elderly. As most pharmacological research within the field of dementia is focused on …

Amyloid beta hypothesis in Alzheimer's disease: major culprits and recent therapeutic strategies

D Vijayan, R Chandra - Current Drug Targets, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the most common forms of dementia and has been a
global concern for several years. Due to the multi-factorial nature of the disease, AD has …