Impact of Mycophenolic Acid on the Functionality of Human Polymorphonuclear Neutrophils and Dendritic Cells during Interaction with Aspergillus fumigatus

M Mezger, I Wozniok, C Blockhaus… - Antimicrobial agents …, 2008 - Am Soc Microbiol
Mycophenolic acid (MPA) is used clinically to prevent graft rejection but may increase the
risk of fungal infection. We observed that MPA enhanced the Aspergillus fumigatus-induced …

Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase

JG Goh, S Ravikumar, MS Win, Q Cao… - Cellular …, 2018 - Wiley Online Library
Invasive aspergillosis (IA) remains a major cause of morbidity in immunocompromised
hosts. This is due to the inability of the host immunity to respond appropriately to Aspergillus …

Detection of invasive aspergillosis in bone marrow transplant recipients using real-time PCR

M Nabili, T Shokohi, G Janbabaie… - Journal of global …, 2013 - journals.lww.com
Objective: The invasive aspergillosis (IA) is a serious opportunistic infection caused by
various species of Aspergillus in immunocompromised individuals. Basically, rapid and …

Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus during Macrophage Cell Death

A Shah, S Kannambath, S Herbst, A Rogers… - American journal of …, 2016 - atsjournals.org
Rationale: Pulmonary aspergillosis is a lethal mold infection in the immunocompromised
host. Understanding initial control of infection and how this is altered in the …

Diagnosis of invasive aspergillosis by tracking Aspergillus-specific T cells in hematologic patients with pulmonary infiltrates

L Potenza, P Barozzi, D Vallerini, R Bosco, C Quadrelli… - Leukemia, 2007 - nature.com
Invasive aspergillosis (IA) is a leading cause of infection-related mortality in hematologic
patients, with death rate ranging from 50 to 90%. 1 The reason for this extremely poor …

Pulmonary immune responses to Aspergillus fumigatus in rats

I Mirkov, AAM El-Muzghi, J Djokic, M Ninkov… - Biomedical and …, 2014 - Elsevier
Objective To evaluate immunologic mechanisms underlying Aspergillus fumigatus
pulmonary infections in immunocompetent Dark Agouti (DA) and Albino Oxford (AO) rats …

[PDF][PDF] Invasive Pulmonary Aspergillosis Successfully Treated with Granulocyte Transfusions Followed by Hematopoietic Stem Cell Transplantation in a Patient with …

D Toyama, M Koganesawa, K Akiyama… - Tokai J Exp Clin …, 2022 - researchgate.net
Granulocyte transfusions (GTX) have been used in patients with neutropenia or neutropenia
associated with invasive fungal infection. An 11-year-old girl with severe aplastic anemia …

Serum cytokines usefulness for understanding the pathology in allergic bronchopulmonary aspergillosis and chronic pulmonary aspergillosis

Y Ito, T Takazono, Y Obase, S Fukahori, N Ashizawa… - Journal of Fungi, 2022 - mdpi.com
Allergic bronchopulmonary aspergillosis (ABPA) and chronic pulmonary aspergillosis (CPA)
are important fungal infections caused by Aspergillus species. An overlap of ABPA and CPA …

Aspergillus fumigatus antigens activate innate immune cells via toll‐like receptors 2 and 4

S Braedel, M Radsak, H Einsele… - British journal of …, 2004 - Wiley Online Library
Invasive aspergillosis (IA) is a leading cause of mortality in haematological patients.
Appropriate activation of the innate immune system is crucial for the successful clearance of …

Apoptosis inhibition of alveolar macrophages upon interaction with conidia of Aspergillus fumigatus

K Volling, AA Brakhage, HP Saluz - FEMS microbiology letters, 2007 - academic.oup.com
The opportunistic human pathogenic fungus Aspergillus fumigatus (Af) causes the majority
of cases of invasive aspergillosis. Because Af enters the human body through inhalation of …