Aspergillosis and stem cell transplantation: An overview of experimental pathogenesis studies

N Al-Bader, DC Sheppard - Virulence, 2016 - Taylor & Francis
Invasive aspergillosis is a life-threatening infection caused by the opportunistic filamentous
fungus Aspergillus fumigatus. Patients undergoing haematopoietic stem cell transplant …

[HTML][HTML] Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

JA Sugui, HS Kim, KA Zarember, YC Chang, JI Gallin… - PLoS …, 2008 - journals.plos.org
Background Aspergillus fumigatus is the most common etiologic agent of invasive
aspergillosis in immunocompromised patients. Several studies have addressed the …

Kinetic host defense of the mice infected with Aspergillus Fumigatus

H Su, C Li, Y Wang, Y Li, L Dong, L Li, J Zhu… - Future …, 2019 - Future Medicine
Aim: Aspergillus fumigatus is one of the most common opportunistic fungi that can cause
invasive infection. To profile the kinetic variation of immune cells and cytokines after …

[HTML][HTML] Neutrophile-to-Lymphocyte Ratio as a Predictor of Mortality and Response to Treatment in Invasive Aspergillosis among Heart Transplant Recipients …

T Urbanowicz, M Michalak, A Olasińska-Wiśniewska… - Medicina, 2021 - mdpi.com
Background and objective: Aspergillus pulmonary infections are potentially life-threatening
complications that can occur after heart transplantation. The aim of the study was to find an …

Clinical-scale generation of human anti-Aspergillus T cells for adoptive immunotherapy

L Tramsen, U Koehl, T Tonn, JP Latge… - Bone marrow …, 2009 - nature.com
Invasive aspergillosis is a major cause of morbidity and mortality in patients undergoing
allogeneic hematopoietic SCT. There is a growing body of evidence that T cells are …

Quantification of phagocytosis of Aspergillus conidia by macrophages using a novel antibody-independent assay

K Luther, M Rohde, J Heesemann, F Ebel - Journal of microbiological …, 2006 - Elsevier
The pathogenic mould Aspergillus fumigatus can cause severe infections in
immunocompromised patients. Phagocytosis of inhaled conidia is an early and crucial event …

Effect of amphotericin B treatment on kinetics of cytokines and parameters of fungal load in neutropenic rats with invasive pulmonary aspergillosis

MJ Becker, S de Marie, MHAM Fens… - Journal of …, 2003 - academic.oup.com
Objective: The kinetics of various parameters of fungal load and cytokines were investigated,
in order to acquire insight into the pathogenesis of invasive pulmonary aspergillosis (IPA) …

Enumeration of functionally active anti-Aspergillus T-cells in human peripheral blood

O Beck, U Koehl, L Tramsen, S Mousset… - Journal of …, 2008 - Elsevier
Invasive aspergillosis remains a life-threatening complication in patients undergoing
allogeneic stem cell transplantation (SCT). Since CD4+ T-cells provide a critical secondary …

[HTML][HTML] Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients

L Potenza, D Vallerini, P Barozzi, G Riva, F Forghieri… - PloS one, 2013 - journals.plos.org
Several studies in mouse model of invasive aspergillosis (IA) and in healthy donors have
shown that different Aspergillus antigens may stimulate different adaptive immune …

Antifungal Activity Of Elutriated Human Monocytes Against Aspergillus Fumigatus Hyphae: Enhancement By Granulocyte-Macrophage Colonystimulating Factor And …

E Roilides, A Holmes, C Blake, D Venzon… - Journal of Infectious …, 1994 - academic.oup.com
Human monocytes are important effector cells in host defenses against Aspergillus hyphae,
and as elutriated monocytes (EHM) they may be transfused in large quantities to leukopenic …