Characterization of telomerase activity in the human oocyte and preimplantation embryo

DL Wright, EL Jones, JF Mayer… - Molecular human …, 2001 - academic.oup.com
Telomerase, a ribonucleoprotein, has been described as an essential component of highly
proliferative cells as it stabilizes the telomeres and avoids cellular senescence. The …

Telomerase activity in bovine embryos during early development

J Xu, X Yang - Biology of reproduction, 2000 - academic.oup.com
The telomere is the end structure of the DNA molecule. Telomerase is the ribonuclear
enzyme that helps the cell's telomere to elongate; otherwise, the telomere will shorten with …

Telomerase activity in female and male rat germ cells undergoing meiosis and in early embryos

KM Eisenhauer, RM Gerstein, CP Chiu… - Biology of …, 1997 - academic.oup.com
Telomerase is a ribonucleoprotein that synthesizes telomeric DNA at the ends of eukaryotic
chromosomes. It has been hypothesized that telomerase activity is necessary for cellular …

Alternative splicing of the telomerase catalytic subunit in human oocytes and embryos

CA Brenner, YM Wolny, RR Adler… - Molecular human …, 1999 - academic.oup.com
The human telomerase catalytic subunit (hTCS) is a ribonucleoprotein which synthesizes
telomere repeats on the ends of chromosomes. Telomerase activity is thought to be …

Expression of telomerase activity in human chorion

S Kyo, M Takakura, M Tanaka, T Kanaya… - Biochemical and …, 1997 - Elsevier
Telomerase activation is required for cellular immortalization and is found in most malignant
tumors. Normal somatic cells are generally telomerase-negative, except for stem cells in …

Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species

S Ozturk, B Sozen, N Demir - Molecular human reproduction, 2014 - academic.oup.com
Telomeres are located at the ends of all eukaryotic chromosomes and protect them from
deleterious events such as inappropriate DNA repair, illegitimate recombination or improper …

Telomerase activity in human germline and embryonic tissues and cells

WE Wright, MA Piatyszek, WE Rainey… - Developmental …, 1996 - Wiley Online Library
Telomerase is a ribonucleoprotein that synthesizes telomere repeats onto chromosome
ends and is involved in maintaining telomere length in germline tissues and in immortal and …

Developmental regulation of telomerase activity in human fetal tissues during gestation.

GA Ulaner, LC Giudice - Molecular human reproduction, 1997 - academic.oup.com
Telomerase is a ribonucleoprotein that adds hexanucleotide repeats (telomeres) to the ends
of linear chromosomes, compensating for the loss of telomeric DNA which occurs with DNA …

Telomere lengths in human oocytes, cleavage stage embryos and blastocysts

S Turner, HP Wong, J Rai… - Molecular human …, 2010 - academic.oup.com
Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA
repair proteins. Telomeres shorten during each cell division in the absence of telomerase …

Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies

RJ Chen, CT Chu, SC Huang, SN Chow… - Human …, 2002 - academic.oup.com
BACKGROUND: The aim of this study was to evaluate telomerase activity in tissue from
cases of gestational trophoblastic disease (GTD) and in placental tissue from early and late …