Characterization of telomerase activity in the human oocyte and preimplantation embryo
DL Wright, EL Jones, JF Mayer… - Molecular human …, 2001 - academic.oup.com
Telomerase, a ribonucleoprotein, has been described as an essential component of highly
proliferative cells as it stabilizes the telomeres and avoids cellular senescence. The …
proliferative cells as it stabilizes the telomeres and avoids cellular senescence. The …
Telomerase activity in bovine embryos during early development
J Xu, X Yang - Biology of reproduction, 2000 - academic.oup.com
The telomere is the end structure of the DNA molecule. Telomerase is the ribonuclear
enzyme that helps the cell's telomere to elongate; otherwise, the telomere will shorten with …
enzyme that helps the cell's telomere to elongate; otherwise, the telomere will shorten with …
Telomerase activity in female and male rat germ cells undergoing meiosis and in early embryos
KM Eisenhauer, RM Gerstein, CP Chiu… - Biology of …, 1997 - academic.oup.com
Telomerase is a ribonucleoprotein that synthesizes telomeric DNA at the ends of eukaryotic
chromosomes. It has been hypothesized that telomerase activity is necessary for cellular …
chromosomes. It has been hypothesized that telomerase activity is necessary for cellular …
Alternative splicing of the telomerase catalytic subunit in human oocytes and embryos
CA Brenner, YM Wolny, RR Adler… - Molecular human …, 1999 - academic.oup.com
The human telomerase catalytic subunit (hTCS) is a ribonucleoprotein which synthesizes
telomere repeats on the ends of chromosomes. Telomerase activity is thought to be …
telomere repeats on the ends of chromosomes. Telomerase activity is thought to be …
Expression of telomerase activity in human chorion
S Kyo, M Takakura, M Tanaka, T Kanaya… - Biochemical and …, 1997 - Elsevier
Telomerase activation is required for cellular immortalization and is found in most malignant
tumors. Normal somatic cells are generally telomerase-negative, except for stem cells in …
tumors. Normal somatic cells are generally telomerase-negative, except for stem cells in …
Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species
Telomeres are located at the ends of all eukaryotic chromosomes and protect them from
deleterious events such as inappropriate DNA repair, illegitimate recombination or improper …
deleterious events such as inappropriate DNA repair, illegitimate recombination or improper …
Telomerase activity in human germline and embryonic tissues and cells
WE Wright, MA Piatyszek, WE Rainey… - Developmental …, 1996 - Wiley Online Library
Telomerase is a ribonucleoprotein that synthesizes telomere repeats onto chromosome
ends and is involved in maintaining telomere length in germline tissues and in immortal and …
ends and is involved in maintaining telomere length in germline tissues and in immortal and …
Developmental regulation of telomerase activity in human fetal tissues during gestation.
GA Ulaner, LC Giudice - Molecular human reproduction, 1997 - academic.oup.com
Telomerase is a ribonucleoprotein that adds hexanucleotide repeats (telomeres) to the ends
of linear chromosomes, compensating for the loss of telomeric DNA which occurs with DNA …
of linear chromosomes, compensating for the loss of telomeric DNA which occurs with DNA …
Telomere lengths in human oocytes, cleavage stage embryos and blastocysts
S Turner, HP Wong, J Rai… - Molecular human …, 2010 - academic.oup.com
Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA
repair proteins. Telomeres shorten during each cell division in the absence of telomerase …
repair proteins. Telomeres shorten during each cell division in the absence of telomerase …
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies
RJ Chen, CT Chu, SC Huang, SN Chow… - Human …, 2002 - academic.oup.com
BACKGROUND: The aim of this study was to evaluate telomerase activity in tissue from
cases of gestational trophoblastic disease (GTD) and in placental tissue from early and late …
cases of gestational trophoblastic disease (GTD) and in placental tissue from early and late …
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