Ferroptosis: a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury

QS Li, YJ Jia - Neural Regeneration Research, 2023 - journals.lww.com
Ferroptosis, a new non-necrotizing programmed cell death (PCD), is driven by iron-
dependent phospholipid peroxidation. Ferroptosis plays a key role in secondary traumatic …

Progress in understanding ferroptosis and its targeting for therapeutic benefits in traumatic brain and spinal cord injuries

X Hu, Y Xu, H Xu, C Jin, H Zhang, H Su, Y Li… - Frontiers in cell and …, 2021 - frontiersin.org
Acute central nervous system (CNS) trauma, including spinal cord injury (SCI) and traumatic
brain injury (TBI), always leads to severe sensory, motor and autonomic nervous system …

Mechanism of ferroptosis and its relationships with other types of programmed cell death: insights for potential therapeutic benefits in traumatic brain injury

Q Pang, L Zheng, Z Ren, H Xu, H Guo… - Oxidative Medicine …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is a serious health issue with a high incidence, high morbidity,
and high mortality that poses a large burden on society. Further understanding of the …

Ferroptosis and traumatic brain injury

Z Geng, Z Guo, R Guo, R Ye, W Zhu, B Yan - Brain Research Bulletin, 2021 - Elsevier
Traumatic brain injury (TBI) is a worldwide health problem contributing to significant
economic burden. TBI is difficult to treat partly due to incomplete understanding of …

Ferroptosis in acute central nervous system injuries: the future direction?

L Shen, D Lin, X Li, H Wu, C Lenahan, Y Pan… - Frontiers in cell and …, 2020 - frontiersin.org
Acute central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI), and
spinal cord injury (SCI) present a grave health care challenge worldwide due to high …

Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in mice

BS Xie, YQ Wang, Y Lin, Q Mao, JF Feng… - CNS neuroscience & …, 2019 - Wiley Online Library
Aims Ferroptosis, a new form of iron‐dependent programmed cell death, has been shown to
be involved in a range of diseases. However, the role of ferroptosis in traumatic brain injury …

Role of ferroptosis in neurological diseases

MY Yao, T Liu, L Zhang, MJ Wang, Y Yang, J Gao - Neuroscience Letters, 2021 - Elsevier
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides which leads to oxidative …

Cross talk between ferroptosis and cerebral ischemia

X She, B Lan, H Tian, B Tang - Frontiers in neuroscience, 2020 - frontiersin.org
Recently, ferroptosis has been revealed as a new form of regulated cell death. Distinct from
apoptosis and necrosis, ferroptosis is evoked by iron-dependent lipid peroxidation …

Ferroptosis in neurological diseases

JX Ren, X Sun, XL Yan, ZN Guo… - Frontiers in Cellular …, 2020 - frontiersin.org
Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is
characterized by glutathione consumption and lipid peroxides accumulation. Ferroptosis is …

The role of ferroptosis in neurodegenerative diseases

Y Xu, J Zhao, Y Zhao, L Zhou, H Qiao, Q Xu… - Molecular Biology …, 2023 - Springer
Ferroptosis is newly identified as a non-apoptotic form of programmed cell death. It is
characterized by iron-dependent intracellular accumulation of lipid peroxides which …