The dichotomous role of the gut microbiome in exacerbating and ameliorating neurodegenerative disorders

U Raval, JM Harary, E Zeng… - Expert review of …, 2020 - Taylor & Francis
Introduction Age related neurodegenerative disorders affect millions of people around the
world. The role of the gut microbiome (GM) in neurodegenerative disorders has been …

[HTML][HTML] Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside

YY Ma, X Li, JT Yu, YJ Wang - Translational Neurodegeneration, 2024 - Springer
The aetiologies and origins of neurodegenerative diseases, such as Alzheimer's disease
(AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's …

The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances

S Li, L Zhao, J Xiao, Y Guo, R Fu, Y Zhang… - Molecular and cellular …, 2023 - Springer
There are complex interactions between the gut and the brain. With increasing research on
the relationship between gut microbiota and brain function, accumulated clinical and …

[PDF][PDF] Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases

EJ Gates, AK Bernath, A Klegeris - Reviews in the Neurosciences, 2022 - degruyter.com
The global prevalence of Alzheimer's disease and Parkinson's disease is steadily increasing
due to the aging population. The lack of effective drugs against these neurodegenerative …

Modification of the gut microbiome to combat neurodegeneration

AO Sasmita - Reviews in the Neurosciences, 2019 - degruyter.com
The gut microbiome was extensively researched for its biological variety and its potential
role in propagating diseases outside of the gastrointestinal (GI) tract. Recently, a lot of effort …

[HTML][HTML] Association of gut microbiome dysbiosis with neurodegeneration: can gut microbe-modifying diet prevent or alleviate the symptoms of neurodegenerative …

LY Tan, XY Yeo, HG Bae, DPS Lee, RC Ho, JE Kim… - Life, 2021 - mdpi.com
The central nervous system was classically perceived as anatomically and functionally
independent from the other visceral organs. But in recent decades, compelling evidence has …

[HTML][HTML] Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration

I Stolzer, E Scherer, P Süß, V Rothhammer… - International Journal of …, 2023 - mdpi.com
The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …

[HTML][HTML] The role of the gut microbiota in neurodegenerative diseases

A Philip Mani, B Balasubramanian, LA Mali… - Microbiology …, 2024 - mdpi.com
The human gut has a rich and dynamic microbial population that plays an important role in
many physiological activities. This review explores the complex interaction between the gut …

Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease

MF Sun, YQ Shen - Ageing research reviews, 2018 - Elsevier
Gut microbial dysbiosis and alteration of microbial metabolites in Parkinson's disease (PD)
have been increasingly reported. Dysbiosis in the composition and abundance of gut …

Influence of the gut microbiota on the development of neurodegenerative diseases

MP Singh, R Chakrabarty, S Shabir… - Mediators of …, 2022 - Wiley Online Library
Neurodegenerative disorders are marked by neuronal death over time, causing a variety of
cognitive and motor dysfunctions. Protein misfolding, neuroinflammation, and mitochondrial …