The rainbow trout Oncorhynchus mykiss interleukin‐1β gene has a different organization to mammals and undergoes incomplete splicing

J Zou, C Cunningham… - European Journal of …, 1999 - Wiley Online Library
The rainbow trout interleukin (IL)‐1β gene consists of six exons/five introns, in contrast to
mammals which have seven exons/six introns. The missing exon appears to be at the 5 …

Modelling of fish interleukin-1 and its receptor

G Scapigliati, S Costantini, G Colonna… - Developmental & …, 2004 - Elsevier
This paper presents original data regarding: the three-dimensional modelling of rainbow
trout (Oncorhynchus mykiss) and sea bass (Dicentrarchus labrax) IL-1β, the modelling of …

Evolution and function analysis of interleukin-17 gene from Pinctada fucata martensii

Y Cao, S Yang, C Feng, W Zhan, Z Zheng… - Fish & Shellfish …, 2019 - Elsevier
Abstract Interleukin-17 (IL-17) is a proinflammatory cytokine that plays an important role in
immune responses. In this study, we identified 57 IL-17 genes from the genomes of six …

Interleukin-6 family cytokine M17 induces differentiation and nitric oxide response of goldfish (Carassius auratus L.) macrophages

PC Hanington, M Belosevic - Developmental & Comparative Immunology, 2007 - Elsevier
Cytokines belonging to the interleukin-6 (IL-6) family function in many biological processes
and display a high degree of redundancy within the family. Although a number of mRNA …

The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus)

HD Perkins, BH van Leeuwen, CM Hardy, PJ Kerr - Cytokine, 2000 - Elsevier
The cDNAs for four rabbit cytokine genes [interleukin 2 (IL-2), IL-4, IL-6 and IL-10] have been
cloned from primary lymphocytes by polymerase chain reaction (PCR) methods. IL-2 and IL …

Cloning and sequence analysis of the interleukin-8 gene from flounder (Paralichthys olivaceous)

EY Lee, HH Park, YT Kim, JK Chung, TJ Choi - Gene, 2001 - Elsevier
A cDNA library of mRNA from flounder leukocytes stimulated with bacterial
lipopolysaccharide (LPS) and hemagglutinin was constructed to clone cytokine genes of this …

Cloning, sequencing, and analysis of expression of a second IL-1 β gene in rainbow trout (Oncorhynchus mykiss)

O Pleguezuelos, J Zou, C Cunningham, CJ Secombes - Immunogenetics, 2000 - Springer
The full-length sequence of a second IL-1 β gene (IL-1 β 2) in rainbow trout (Oncorhynchus
mykiss) has been obtained. As with the first IL-1 β gene, IL-1 β 2 is organized into six …

Cloning and characterization of the Rainbow trout (Oncorhynchus mykiss) type II interleukin‐1 receptor cDNA

A Sangrador‐Vegas, SAM Martin… - European journal of …, 2000 - Wiley Online Library
A homologue of mammalian type II interleukin‐1 receptor (IL‐1RII) was isolated from a
rainbow trout cDNA library by differential hybridization using a suppression subtractive …

Differential expression, modulation and bioactivity of distinct fish IL‐12 isoforms: Implication towards the evolution of Th1‐like immune responses

T Wang, M Husain, S Hong… - European journal of …, 2014 - Wiley Online Library
IL‐12 is a heterodimeric cytokine composed of an α‐chain (p35) and a β‐chain (p40).
Primarily produced by APCs, IL‐12 induces IFN‐γ production in T, B and NK cells. IL‐12 …

Invertebrate cytokines: The phylogenetic emergence of interleukin‐1

G Beck, RF O'Brien, GS Habicht - BioEssays, 1989 - Wiley Online Library
Cytokines are polypeptides released by activated vertebrate blood cells which have
profound effects on other blood cells and which have hormone‐like properties affecting …