The neoadjuvant therapy of colorectal hepatic metastases and the role of biologic sensitizing and resistance factors
HJ Wanebo, D Berz - Journal of Surgical Oncology, 2010 - Wiley Online Library
Liver metastasis represents a common systemic complication of colorectal cancers (CRCs).
Partial liver resection has been demonstrated to result in long‐term survival in certain well …
Partial liver resection has been demonstrated to result in long‐term survival in certain well …
The effect of preoperative chemotherapy on liver regeneration after portal vein embolization/ligation or liver resection in patients with colorectal liver metastasis: a …
MC Pavel, R Casanova, L Estalella, R Memba… - Systematic …, 2020 - Springer
Introduction Liver resection (LR) in patients with liver metastasis from colorectal cancer
remains the only curative treatment. Perioperative chemotherapy improves prognosis of …
remains the only curative treatment. Perioperative chemotherapy improves prognosis of …
The issue of survival after colorectal liver metastasis surgery: parenchyma sparing vs. radicality
A Palkovics, A Vereczkei, KN Kalmar… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Nowadays, obtaining optimal surgical margin of the resected metastasis
and the parenchyma-sparing surgical technique are a great challenge for hepatic surgeons …
and the parenchyma-sparing surgical technique are a great challenge for hepatic surgeons …
Blocking transforming growth factor–beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells
E Fransvea, U Angelotti, S Antonaci, G Giannelli - Hepatology, 2008 - journals.lww.com
Hepatocellular carcinoma (HCC) treatment is challenging because the mechanisms
underlying tumor progression are still largely unknown. Transforming growth factor (TGF) …
underlying tumor progression are still largely unknown. Transforming growth factor (TGF) …
Inhibitory CpG sequences reduced ischemia/reperfusion-induced hepatic metastases of liver tumor in a murine model
J Wang, Y Liu, A Zhang, C Li, J Dong - journal of surgical research, 2012 - Elsevier
BACKGROUND: It is reported that hepatic ischemia/reperfusion (I/R) during hepatectomy
accelerates liver tumor growth. Hepatic I/R induces inflammation cytokines, which can …
accelerates liver tumor growth. Hepatic I/R induces inflammation cytokines, which can …
Chemotherapy can promote liver metastasis by enhancing metastatic niche formation in mice
M Zenitani, T Nojiri, H Hosoda, T Kimura… - Journal of Surgical …, 2018 - Elsevier
Background Some chemotherapeutic agents have been reported to promote lung
metastasis. However, there have been no reports regarding chemotherapy-induced liver …
metastasis. However, there have been no reports regarding chemotherapy-induced liver …
Preoperative chemotherapy for colorectal liver metastases: impact on hepatic histology and postoperative outcome
TM Pawlik, K Olino, AL Gleisner, M Torbenson… - Journal of …, 2007 - Elsevier
Some investigators have suggested that preoperative chemotherapy for hepatic colorectal
metastases may cause hepatic injury and increase perioperative morbidity and mortality …
metastases may cause hepatic injury and increase perioperative morbidity and mortality …
Maximal debulking liver resection as a beneficial treatment strategy for advanced and aggressive colorectal liver metastases
K Tanaka, T Murakami, Y Yabushita… - Anticancer …, 2014 - ar.iiarjournals.org
Background: A survival benefit is generally considered unobtainable following incomplete
hepatic resection in patients with colorectal liver metastases. However, this question should …
hepatic resection in patients with colorectal liver metastases. However, this question should …
Ischemia–Reperfusion Injury and Regrowth of Liver Cancers: To Clamp or Not to Clamp?
C Lim, D Azoulay - Digestive Diseases and Sciences, 2014 - Springer
Although resection remains the only potentially curative treatment for most patients with
primary and secondary liver malignancies, the large majority of patients will experience …
primary and secondary liver malignancies, the large majority of patients will experience …
An in vivo rat model for early development of colorectal cancer metastasis to liver
JHP Robertson, SY Yang, AM Iga… - International Journal …, 2008 - Wiley Online Library
At diagnosis of colorectal cancer, approximately 25% of the patients have established
colorectal liver metastasis. Optimal management of disseminated disease requires therapies …
colorectal liver metastasis. Optimal management of disseminated disease requires therapies …