Improving outcomes for solid-organ transplant recipients at risk from cytomegalovirus infection: late-onset disease and indirect consequences

C Legendre, M Pascual - Clinical infectious diseases, 2008 - academic.oup.com
Cytomegalovirus (CMV) is one of the most important pathogens following solid-organ
transplantation, and effective prevention of CMV infection is a priority. The long-term control …

Prevention of cytomegalovirus disease in recipients of solid-organ transplants

DR Snydman, CV Paya - Clinical infectious diseases, 2001 - academic.oup.com
The introduction and combination of more-potent immunosuppressive regimens, and the
increased transplantation of organs into more severely ill patients, have again placed …

Cytomegalovirus infection and disease in the new era of immunosuppression following solid organ transplantation

RA Fisher - Transplant Infectious Disease, 2009 - Wiley Online Library
As the most prevalent pathogen among transplant patients, cytomegalovirus (CMV) affects
up to three‐quarters of all solid organ transplant recipients. While we have made great …

The impact of the prevention strategies on the indirect effects of CMV infection in solid organ transplant recipients

A Roman, N Manito, JM Campistol… - Transplantation …, 2014 - Elsevier
Transplant recipients receiving immunosuppressive therapy are at increased risk of active
cytomegalovirus (CMV) infection and disease. Without appropriate prophylaxis, as many as …

Cytomegalovirus in transplantation – challenging the status quo

JA Fishman, V Emery, R Freeman… - Clinical …, 2007 - Wiley Online Library
Background: Cytomegalovirus (CMV) infection of solid organ transplant (SOT) recipients
causes both ''direct''and ''indirect''effects including allograft rejection, decreased graft and …

Viral load, CMV‐specific T‐cell immune response and cytomegalovirus disease in solid organ transplant recipients at higher risk for cytomegalovirus infection during …

C Martín‐Gandul, P Pérez‐Romero… - Transplant …, 2014 - Wiley Online Library
Despite advances in prevention, cytomegalovirus (CMV) recurrence is an important
challenge in high‐risk organ recipients. The present study prospectively evaluates the …

[HTML][HTML] Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients

O Manuel, G Kralidis, NJ Mueller, HH Hirsch… - American journal of …, 2013 - Elsevier
We assessed the impact of antiviral prophylaxis and preemptive therapy on the incidence
and outcomes of cytomegalovirus (CMV) disease in a nationwide prospective cohort of solid …

Cytomegalovirus infection in solid organ transplant recipients: new challenges and their implications for preventive strategies

N Singh - Journal of clinical virology, 2006 - Elsevier
BACKGROUND: Late-onset CMV disease is being increasingly recognized as a significant
post-transplantation complication. OBJECTIVES: To discern the impact of antiviral …

[引用][C] It's not too late: a proposal to standardize the terminology of “late‐onset” cytomegalovirus infection and disease in solid organ transplant recipients

RR Razonable, EA Blumberg - Transplant Infectious Disease, 2015 - Wiley Online Library
Despite remarkable improvements in its diagnosis, prevention, and treatment,
cytomegalovirus (CMV) remains the single most important pathogen after solid organ …

Strategies for managing cytomegalovirus in transplant recipients

RR Razonable - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: Cytomegalovirus (CMV) is the most important pathogen that affects
transplant recipients, by directly causing clinical disease and by indirectly reducing patient …