Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy
MJH Coenen, JM Hofstra, H Debiec… - Journal of the …, 2013 - journals.lww.com
The M-type receptor for phospholipase A2 (PLA2R1) is the major target antigen in idiopathic
membranous nephropathy (iMN). Our recent genome-wide association study showed that …
membranous nephropathy (iMN). Our recent genome-wide association study showed that …
[HTML][HTML] Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy
D Kanigicherla, J Gummadova, EA McKenzie… - Kidney international, 2013 - Elsevier
Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …
Single Nucleotide Polymorphisms in the Phospholipase A2 Receptor Gene Are Associated with Genetic Susceptibility to Idiopathic Membranous Nephropathy
Background: The phospholipase A2 receptor (PLA2R) is a major antigen found in patients
with idiopathic membranous nephropathy (MN). The relationship of genetic polymorphisms …
with idiopathic membranous nephropathy (MN). The relationship of genetic polymorphisms …
PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians
Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …
Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy
J Lv, W Hou, X Zhou, G Liu, F Zhou… - Journal of the …, 2013 - journals.lww.com
Risk alleles at genome loci containing phospholipase A2 receptor 1 (PLA2R1) and HLA-
DQA1 closely associate with idiopathic membranous nephropathy (IMN) in the European …
DQA1 closely associate with idiopathic membranous nephropathy (IMN) in the European …
Epitope spreading of autoantibody response to PLA2R associates with poor prognosis in membranous nephropathy
B Seitz-Polski, G Dolla, C Payré… - Journal of the …, 2016 - journals.lww.com
The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …
Clinical relevance of domain-specific phospholipase A2 receptor 1 antibody levels in patients with membranous nephropathy
L Reinhard, G Zahner, S Menzel… - Journal of the …, 2020 - journals.lww.com
Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …
of patients with membranous nephropathy, and previous studies described three …
PLA2R-associated membranous glomerulopathy is modulated by common variants in PLA2R1 and HLA-DQA1 genes
M Saeed, ML Beggs, PD Walker, CP Larsen - Genes & Immunity, 2014 - nature.com
Membranous glomerulopathy (MG) is most commonly caused by autoantibodies directed
against the podocyte phospholipase A2 receptor (PLA2R1) and common variants in this …
against the podocyte phospholipase A2 receptor (PLA2R1) and common variants in this …
Genetics of membranous nephropathy
S Gupta, A Köttgen, E Hoxha… - Nephrology Dialysis …, 2018 - academic.oup.com
An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and
additional evidence for a genetic component to MN was suggested in 1984 in reports of …
additional evidence for a genetic component to MN was suggested in 1984 in reports of …
[HTML][HTML] Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan
Background Idiopathic membranous nephropathy (IMN) is one of the most common forms of
autoimmune nephritic syndrome in adults. The purpose of this study is to evaluate whether …
autoimmune nephritic syndrome in adults. The purpose of this study is to evaluate whether …