Anti-phospholipase A2 receptor antibody titer predicts post-rituximab outcome of membranous nephropathy

P Ruggenenti, H Debiec, B Ruggiero… - Journal of the …, 2015 - journals.lww.com
Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary
membranous nephropathy (MN), even after other treatments have failed. To assess the …

Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy

C Dähnrich, L Komorowski, C Probst, B Seitz-Polski… - Clinica Chimica …, 2013 - Elsevier
BACKGROUND: Autoantibodies against the M-type phospholipase A2 receptor (PLA2R1)
are specific markers for primary membranous nephropathy (pMN) and anti-PLA2R1 serum …

[HTML][HTML] Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy

E Hoxha, U Kneißler, G Stege, G Zahner, I Thiele… - Kidney international, 2012 - Elsevier
The M-type phospholipase A2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy with detectable autoantibodies in the serum of up to 70% of …

Phospholipase A2 receptor autoantibodies and clinical outcome in patients with primary membranous nephropathy

E Hoxha, I Thiele, G Zahner, U Panzer… - Journal of the …, 2014 - journals.lww.com
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults,
with an uncertain clinical outcome. The characterization of the phospholipase A 2 receptor …

Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: a cross-sectional study

L Pang, AM Zhang, HX Li, JL Du, LL Jiao, N Duan… - Medicine, 2017 - journals.lww.com
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary
membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of …

The Role of PLA2R in Primary Membranous Nephropathy: Do We Still Need a Kidney Biopsy?

T McDonnell, HHL Wu, S Sinha, R Chinnadurai - Genes, 2023 - mdpi.com
Membranous nephropathy (MN) is the most prevalent cause of nephrotic syndrome amongst
the non-diabetic adult population. A fifth of idiopathic nephrotic syndrome cases can be …

Ultrasensitive quantitation of anti-phospholipase A2 receptor antibody as a diagnostic and prognostic indicator of idiopathic membranous nephropathy

Q Zhang, B Huang, X Liu, B Liu, Y Zhang, Z Zhang… - Scientific Reports, 2017 - nature.com
Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful for affirming the diagnosis of
idiopathic membranous nephropathy (IMN). Time-resolved fluoroimmunoassay (TRFIA) is …

Serum anti-PLA2R antibody as a diagnostic biomarker of idiopathic membranous nephropathy: the optimal cut-off value for Chinese patients

Y Liu, X Li, C Ma, P Wang, J Liu, H Su, H Zhuo… - Clinica Chimica …, 2018 - Elsevier
Background The M-type phospholipase A2 receptor (PLA2R) is a specific target autoantigen
identified in idiopathic membranous nephropathy (IMN). The autoantibody against PLA2R …

Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy

LN Cossey, PD Walker, CP Larsen - Pediatric Nephrology, 2013 - Springer
Background Membranous glomerulopathy, though typically a disease of adults, does occur
in children. Antiphospholipase A2 receptor (PLA2R) autoantibodies have recently been …

[HTML][HTML] Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy

EJ Song, KH Jeong, YA Yang, JH Lim… - Kidney research and …, 2018 - ncbi.nlm.nih.gov
Background Phospholipase A2 receptor (PLA2R) has been identified as a major
autoantigen in primary membranous nephropathy (MN). We evaluated the association …