Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory
stimuli and circuits and has poor reparative potential. Despite progress in our understanding …
stimuli and circuits and has poor reparative potential. Despite progress in our understanding …
[HTML][HTML] The noncoding-RNA landscape in cardiovascular health and disease
V Di Mauro, M Barandalla-Sobrados… - Non-coding RNA …, 2018 - Elsevier
The cardiovascular system plays a pivotal role in regulating and maintaining homeostasis in
the human body. Therefore any alteration in regulatory networks that orchestrate heart …
the human body. Therefore any alteration in regulatory networks that orchestrate heart …
Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …
[HTML][HTML] Non-coding RNAs: the “dark matter” of cardiovascular pathophysiology
Large-scale analyses of mammalian transcriptomes have identified a significant number of
different RNA molecules that are not translated into protein. In fact, the use of new …
different RNA molecules that are not translated into protein. In fact, the use of new …
[HTML][HTML] Extracellular non-coding RNAs in cardiovascular diseases
Z Jiapaer, C Li, X Yang, L Sun, E Chatterjee, L Zhang… - Pharmaceutics, 2023 - mdpi.com
Cardiovascular diseases (CVDs) remain the world's leading cause of death despite the best
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …
Long noncoding RNAs in cardiovascular pathology, diagnosis, and therapy
Vast parts of mammalian genomes encode for transcripts that are not further translated into
proteins. The purpose of the majority of such noncoding ribonucleic acids (RNAs) remained …
proteins. The purpose of the majority of such noncoding ribonucleic acids (RNAs) remained …
Non-coding RNAs and ischemic cardiovascular diseases
Abstract The Ischemic Heart Disease (IHD) is considered a clinical condition characterized
by myocardial ischemia causing an imbalance between myocardial blood supply and …
by myocardial ischemia causing an imbalance between myocardial blood supply and …
[HTML][HTML] Deciphering non-coding RNAs in cardiovascular health and disease
After being long considered as “junk” in the human genome, non-coding RNAs (ncRNAs)
currently represent one of the newest frontiers in cardiovascular disease (CVD) since they …
currently represent one of the newest frontiers in cardiovascular disease (CVD) since they …
Noncoding RNAs in cardiovascular diseases
P Gurha - Current opinion in cardiology, 2019 - journals.lww.com
Noncoding RNA provides a versatile mechanism of gene regulation and thereby present as
novel targets for intervention in various cardiovascular disease. Future studies aimed at …
novel targets for intervention in various cardiovascular disease. Future studies aimed at …
[HTML][HTML] Long non-coding RNAs: at the heart of cardiac dysfunction?
During the past decade numerous studies highlighted the importance of long non-coding
RNAs (lncRNAs) in orchestrating cardiovascular cell signaling. Classified only by a …
RNAs (lncRNAs) in orchestrating cardiovascular cell signaling. Classified only by a …