The prevalence of obesity has dramatically increased in recent years and now includes a
significant proportion of the world's children, adolescents and adults. Obesity is linked to a …

Introduction: The prevalence of obesity and associated co-morbid conditions is increasing
globally. Physiological changes accompanying obesity are likely to result in altered drug …

Obesity is a disease characterized as a condition resulting from the excess accumulation of
body fat. In conjunction with increased stores of body fat, obesity has also been associated …

Obesity is a worldwide problem, with major health, social and economic implications. The
adaptation of drug dosages to obese patients is a subject of concern, particularly for drugs …

Obesity is common enough to constitute a serious medical and public health problem. Drug
prescription for obese patients is difficult since dosages based on pharmacokinetic data …

Obesity is a pathophysiological state defined by a body mass index> 30 kg/m 2 and
characterized by an adipose tissue accumulation leading to an important weight increased …

Drug disposition for many drugs has now been studied in obese individuals and some
general conclusions can be drawn. Absorption of drugs evaluated to date is unchanged due …

Introduction: The rising prevalence of obesity confronts clinicians with dosing problems in
the (extreme) overweight population. Obesity has a great impact on key organs that play a …

The prevalence of obesity in the western world is dramatically rising, with many of these
individuals requiring therapeutic intervention for a variety of disease states. Despite the …

Introduction Obesity is associated with many physiological changes. We review available
evidence regarding five commonly accepted assumptions to a priori predict the impact of …