Sir, Recently, Bannwarth et al.(2014) reported a family with a mitochondrial DNA instability
disorder that variably presented with cerebellar ataxia and myopathy but also with an ALS …

Sir, Emerging data provide evidence for CHCHD10 as a new candidate gene in familial
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)(Bannwarth et al …

Objective After the initial report of a CHCHD10 mutation in mitochondrial disease with
features resembling amyotrophic lateral sclerosis (ALS), CHCHD10 mutations have been …

Recently, we provided genetic basis showing that mitochondrial dysfunction can trigger
motor neuron degeneration, through identification of CHCHD10 encoding a mitochondrial …

Sir, A recent study by Bannwarth and colleagues has shown that variation in the CHCHD10
gene is a cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia …

CHCHD10 mutations are linked to amyotrophic lateral sclerosis, but their mode of action is
unclear. In a 29‐year‐old patient with rapid disease progression, we discovered a novel …

Sir, We read with interest the paper recently published in Brain (Bannwarth et al., 2014)
reporting a mutation in CHCHD10 (c. 176C> T, p. Ser59Leu) in familial amyotrophic lateral …

Mutations in the coiled-coil-helix-coiled-coil-helix domain-containing protein 10 gene
(CHCHD10), involved in mitochondrial function, have recently been reported as a causative …

Mutations in CHCHD10, coding for a mitochondrial intermembrane space protein, are a rare
cause of autosomal dominant amyotrophic lateral sclerosis. Mutation-specific toxic gain of …

Mitochondrial DNA instability disorders are responsible for a large clinical spectrum, among
which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are …