[引用][C] Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content

S de Roock, AJ Stoppelenburg, R Scholman… - Journal of Allergy and …, 2013 - jacionline.org
TH17 and Treg cells have a reciprocal development pathway. 5 Both cells play an important
role in the induction and perpetuation of inflammatory responses during infection, and also …

TH17 differentiation capacity develops within the first 3 months of life

KK Dijkstra, SBEA Hoeks, BJ Prakken… - Journal of Allergy and …, 2014 - jacionline.org
FIG 1. Until age 12 months, most TH cells remain naive and most FOXP31 cells are resting
Treg cells found in population I. After thawing, PBMCs were stained for CD3, CD4, CD45RA …

Glucocorticoids promote intrinsic human TH17 differentiation

J de Castro Kroner, K Knoke, DM Kofler… - Journal of Allergy and …, 2018 - jacionline.org
To the Editor: Although TH17 cells are critical to host protection at epithelial barriers, they
also play a pathogenic role in inflammatory and autoimmune diseases. Glucocorticoids are …

Human TH17 cell development requires processing of dendritic cell–derived CXCL8 by neutrophil elastase

Y Souwer, TG Kormelink… - Journal of Allergy and …, 2018 - jacionline.org
To the Editor: IL-17–producing effector CD4 1 helper T cells (TH17 cells) have been
identified as crucial cells in the defense against pathogens such as bacteria and fungi …

T cells in health and disease

CA Akdis - Journal of Allergy and Clinical Immunology, 2009 - jacionline.org
Various populations of effector and regulatory T (Treg) cells have been shown to play a
central role in chronic inflammation in various diseases, the maintenance of peripheral …

Regulation of TH17 markers early in life through maternal farm exposure

A Lluis, N Ballenberger, S Illi, M Schieck… - Journal of Allergy and …, 2014 - Elsevier
Background Previous studies suggested that maternal farm exposure during pregnancy
modulates early immune development toward an allergy-protective status potentially …

Role of TGF-β in anti-rhinovirus immune responses in asthmatic patients

C Bielor, N Sopel, A Maier, A Blau… - Journal of Allergy and …, 2017 - jacionline.org
LETTERS TO THE EDITOR 283 rhinovirus expressed increased levels of TGFBRII
compared with the respective controls (Fig 2, C). This finding suggests that rhinovirus …

Participation of Th17 and Treg cells in pediatric bronchial asthma

Y Yamamoto, T Negoro, A Wakagi, A Hoshi… - Journal of health …, 2010 - jstage.jst.go.jp
The immune response plays an important role in the development of allergic diseases. It is
established that a complex network of various immunocytes such as Th2, non-Th2 (Th17) …

RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease

J de Wit, MH Al-Mossawi, MH Hühn… - Journal of Allergy and …, 2016 - jacionline.org
RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel
disease and proliferation of OT-II CD4 1 T cells when cocultured with OVA-stimulated …

Identification of a novel subset of human circulating memory CD4+ T cells that produce both IL-17A and IL-4

L Cosmi, L Maggi, V Santarlasci, M Capone… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: IL-17A has been suggested to play a pathogenic role in bronchial asthma
and other allergic disorders. OBJECTIVE: Study of the relationship between human IL-17A …