Although the effectiveness of diltiazem for the treatment of patients with hypertension has
been well demonstrated in numerous placebo-controlled and comparative clinical trials …

Although calcium channel blockers were only recently approved for antihypertensive
therapy, 10 years of data have demonstrated their beneficial effects. Among the available …

The objective was to evaluate the dose-related efficacy/tolerance profile of 240, 300, 360,
and 420 mg diltiazem slow-release, once-daily (OD) doses, with emphasis on the 300 mg …

The tablet formulation of diltiazem has been available for the treatment of angina pectoris
but has not been comprehensively evaluated in hypertension. This study's aim was to …

The safety and efficacy of an extended-release form of diltiazem HCl (diltiazem XR) in
patients 55 years or older with mild-to-moderate essential hypertension were examined in a …

Calcium‐channel blockers are a safe and effective treatment modality and have been used
extensively in the treatment of angina and hypertension. Dilacor™ XR capsules, a new …

In a double-blind study, patients with mild-to-moderate hypertension were randomly
assigned to receive placebo or increasing daily doses of a new sustained-release …

Graded extended‐release diltiazem (CARDIZEM® LA)(GRD) is a new formulation of
diltiazem engineered to provide more precise blood pressure control than traditional …

This study assessed once-daily sustained-release (od SR) diltiazem in essential
hypertension; 158 patients with supine diastolic blood pressures (BP) of 95-115 mm Hg …

Background: The efficacy and safety of a chronotherapeutic, graded-release diltiazem HCl
extended-release (GRD) 120-, 240-, 360-and 540-mg dose administered once-daily at …