Opposite effect of simple tetrahydroisoquinolines on amphetamine-and morphine-stimulated locomotor activity in mice
J Vetulani, I Nalepa, L Antkiewicz-Michaluk… - Journal of neural …, 2001 - Springer
Endogenous tetrahydroisoquinolines, such as 1, 2, 3, 4-tetrahydroisoquinoline (TIQ) and 1-
methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (salsolinol), were tested for their …
methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (salsolinol), were tested for their …
A possible physiological role for cerebral tetrahydroisoquinolines
J Vetulani, L Antkiewicz-Michaluk, I Nalepa… - Neurotoxicity …, 2003 - Springer
Tetrahydroisoquinolines present in the mammalian brain, 1, 2, 3, 4-tetrahydroisoquinoline
(TIQ) and salsolinol, suspected to cause neurodegeneration leading to Parkinson's disease …
(TIQ) and salsolinol, suspected to cause neurodegeneration leading to Parkinson's disease …
Antidopaminergic effects of 1, 2, 3, 4-tetrahydroisoquinoline and salsolinol
L Antkiewicz-Michaluk, J Michaluk, I Romańska… - Journal of neural …, 2000 - Springer
Immediate behavioral and biochemical effects of single doses of 1, 2, 3, 4-
tetrahydroisoquinoline (TIQ, 50 mg/kg) and salsolinol (100 mg/kg), suspected of involvement …
tetrahydroisoquinoline (TIQ, 50 mg/kg) and salsolinol (100 mg/kg), suspected of involvement …
Hyperactivity induced by tetrahydroisoquinoline derivatives injected into the nucleus accumbens
B Costall, RJ Naylor, RM Pinder - European Journal of Pharmacology, 1976 - Elsevier
Several derivatives of tetrahydroisoquinoline were injected bilaterally into the nucleus
accumbens of rat 2 h after a nialamide pretreatment and activity recorded in cages fitted with …
accumbens of rat 2 h after a nialamide pretreatment and activity recorded in cages fitted with …
[HTML][HTML] The effect of an endogenous compound 1-methyl-1, 2, 3, 4,-tetrahydroisoquinoline on morphine-induced analgesia, dependence and neurochemical changes …
A Wasik, I Romanska… - Journal of Physiology and …, 2007 - jpp.krakow.pl
1, 2, 3, 4-Tetrahydroisoquinolines, among them the most interesting neuroprotective
substance, an inhibitor of MAO, 1-methyl-1, 2, 3, 4-tetrahydroisoquinoline (1MeTIQ), are …
substance, an inhibitor of MAO, 1-methyl-1, 2, 3, 4-tetrahydroisoquinoline (1MeTIQ), are …
Attenuation of the locomotor activating effects of D-amphetamine, cocaine, and scopolamine by potassium channel modulators
S Rosenzweig-Lipson, S Thomas, JE Barrett - Progress in Neuro …, 1997 - Elsevier
1. Locomotor activating effects of d-amphetamine, cocaine, and scopolamine were
determined alone and after pretreatment with K-channel modulators in mice. 2. 2. When …
determined alone and after pretreatment with K-channel modulators in mice. 2. 2. When …
Inhibition of dopamine receptors by endogenous amines: binding to striatal receptors and pharmacological effects on locomotor activity
H Kawai, Y Kotake, S Ohta - Bioorganic & medicinal chemistry letters, 2000 - Elsevier
Endogenous amine 1-benzyl-1, 2, 3, 4-tetrahydroisoquinoline (1BnTIQ) derivatives are
synthesized, and their activity for dopaminergic systems are evaluated in vitro and in vivo by …
synthesized, and their activity for dopaminergic systems are evaluated in vitro and in vivo by …
Different action on dopamine catabolic pathways of two endogenous 1, 2, 3, 4‐tetrahydroisoquinolines with similar antidopaminergic properties
L Antkiewicz‐Michaluk, J Michaluk… - Journal of …, 2001 - Wiley Online Library
The effect of single and multiple 1‐methyl‐1, 2, 3, 4‐tetrahydroisoquinoline (1MeTIQ) and 1‐
benzyl‐1, 2, 3, 4‐tetrahydroisoquinoline (1BnTIQ) administration on concentrations of …
benzyl‐1, 2, 3, 4‐tetrahydroisoquinoline (1BnTIQ) administration on concentrations of …
1-Methyl-1, 2, 3, 4-tetrahydroisoquinoline antagonizes a rise in brain dopamine metabolism, glutamate release in frontal cortex and locomotor hyperactivity produced …
M Pietraszek, J Michaluk, I Romańska, A Wąsik… - Neurotoxicity …, 2009 - Springer
Methyl-1, 2, 3, 4-tetrahydroisoquinoline (1MeTIQ) is an endogenous compound that is
constantly present in the brain, and that exhibits neuroprotective activity. Our earlier study …
constantly present in the brain, and that exhibits neuroprotective activity. Our earlier study …
Neurochemical changes induced by acute and chronic administration of 1, 2, 3, 4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain
L Antkiewicz-Michaluk, I Romanska, I Papla, J Michaluk… - Neuroscience, 2000 - Elsevier
The finding that endogenous tetrahydroisoquinolines may be involved in the etiology of
Parkinson's disease suggests that their administration may cause changes resembling those …
Parkinson's disease suggests that their administration may cause changes resembling those …