[引用][C] Bacterial gene regulation and transcriptional networks

MM Babu - 2013 - Horizon Scientific Press

Activation and Repression of Transcription at the Double Tandem Divergent Promoters for the xylR and xylS Genes of the TOL Plasmid of Pseudomonas putida

S Marqués, MT Gallegos, M Manzanera… - Journal of …, 1998 - Am Soc Microbiol
The xylR and xylS genes are divergent and control transcription of the TOL plasmid
catabolic pathways for toluene metabolism. Four promoters are found in the 300-bp …

Mechanisms and evolution of control logic in prokaryotic transcriptional regulation

SAFT van Hijum, MH Medema… - … and Molecular Biology …, 2009 - Am Soc Microbiol
SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Design and development of a novel genetic probe for the analysis of repressor–operator interactions

JF Love, JR Murphy - Journal of microbiological methods, 2002 - Elsevier
While the native diphtheria tox promoter/operator (toxPO)-lacZ transcriptional fusion has
allowed initial isolation and characterization of the diphtheria toxin repressor (DtxR), the low …

Transcription factor function and promoter architecture govern the evolution of bacterial regulons

JC Perez, EA Groisman - Proceedings of the National …, 2009 - National Acad Sciences
Evolutionary changes in ancestral regulatory circuits can bring about phenotypic differences
between related organisms. Studies of regulatory circuits in eukaryotes suggest that these …

Transcription factor levels enable metabolic diversification of single cells of environmental bacteria

R Guantes, I Benedetti, R Silva-Rocha… - The ISME …, 2016 - academic.oup.com
Transcriptional noise is a necessary consequence of the molecular events that drive gene
expression in prokaryotes. However, some environmental microorganisms that inhabit …

Activation of the Pseudomonas TOL plasmid upper pathway operon. Identification of binding sites for the positive regulator XylR and for integration host factor protein

MA Abril, M Buck, JL Ramos - Journal of Biological Chemistry, 1991 - ASBMB
Expression of the Pseudomonas putida TOL plasmid upper pathway operon requires a
promoter that belongs to the-12/-24 class. Stimulation of transcription from this promoter is …

Machine-learning from Pseudomonas putida KT2440 transcriptomes reveals its transcriptional regulatory network

HG Lim, K Rychel, AV Sastry, GJ Bentley, J Mueller… - Metabolic …, 2022 - Elsevier
Bacterial gene expression is orchestrated by numerous transcription factors (TFs).
Elucidating how gene expression is regulated is fundamental to understanding bacterial …

Functional domains of the TOL plasmid transcription factor XylS

N Kaldalu, U Toots, V de Lorenzo… - Journal of bacteriology, 2000 - Am Soc Microbiol
The alkylbenzoate degradation genes of Pseudomonas putida TOL plasmid are positively
regulated by XylS, an AraC family protein, in a benzoate-dependent manner. In this study …

Interplay between network structures, regulatory modes and sensing mechanisms of transcription factors in the transcriptional regulatory network of E. coli

S Balaji, MM Babu, L Aravind - Journal of Molecular Biology, 2007 - Elsevier
Though the bacterial transcription regulation apparatus is distinct in terms of several
structural and functional features from its eukaryotic counterpart, the gross structure of the …