In vitro activities of an N-terminal truncated form of XylR, a σ54-dependent transcriptional activator of Pseudomonas putida

J Pérez-Martı́n, V de Lorenzo - Journal of molecular biology, 1996 - Elsevier
A truncated derivative of the XylR protein, which is able to constitutively activate the σ54-
dependentPupromoter of the TOL (toluene biodegradation) plasmid ofPseudomonas putida …

Contrasting signal transduction mechanisms in bacterial and eukaryotic gene transcription

P Cashin, L Goldsack, D Hall… - FEMS microbiology …, 2006 - academic.oup.com
All known cell types use signal transduction systems to respond to an extracellular or
intracellular event. The role of these systems can be to adapt to environmental changes or …

[引用][C] Two-component regulatory systems in prokaryotes

DE Whitworth, A Filloux - Bacterial …, 2012 - Caister Academic Press Norfolk, UK

Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in Pseudomonas

J Trouillon, M Ragno, V Simon, I Attrée, S Elsen - Msystems, 2021 - Am Soc Microbiol
Transcription factors (TFs) are instrumental in the bacterial response to new environmental
conditions. They can act as direct signal sensors and subsequently induce changes in gene …

Regulatory noise in prokaryotic promoters: how bacteria learn to respond to novel environmental signals

V De Lorenzo, J Pérez‐Martín - Molecular microbiology, 1996 - Wiley Online Library
Various features of the regulation of pathways for biodegradation of recalcitrant compounds
by Pseudomonas provide insights into the mechanisms by which operons evolve to acquire …

The organization of the Pm promoter of the TOL plasmid reflects the structure of its cognate activator protein XylS

B Kessler, KN Timmis, V de Lorenzo - Molecular and General Genetics …, 1994 - Springer
The toluate catabolic operon carried by the TOL plasmid pWWO of Pseudomonas putida is
positively regulated by the benzoate-responsive XylS protein which, when activated …

Transcriptional control of the Pseudomonas putida TOL plasmid catabolic pathways

S Marqués, JL Ramos - Molecular microbiology, 1993 - Wiley Online Library
TOL plasmid pWWO of Pseudomonas putida contains two operons that specify a pathway
for the degradation of aromatic hydrocarbons. The upper pathway operon encodes the …

Rational design of a bacterial transcriptional cascade for amplifying gene expression capacity

A Cebolla, C Sousa, V Lorenzo - Nucleic acids research, 2001 - academic.oup.com
Cascade regulatory circuits have been described that control numerous cell processes, and
may provide models for the design of artificial circuits with novel properties. Here we …

Signal transduction meets systems biology: deciphering specificity determinants for protein–protein interactions

RB Bourret - Molecular microbiology, 2008 - Wiley Online Library
Two recent papers (Gao et al. 2008 and Skerker et al. 2008) describe investigations into the
specificity of protein–protein interactions that occur during signal transduction by two …

Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains

S Fernández, V De Lorenzo… - Molecular …, 1995 - Wiley Online Library
In the presence of toluene, xylenes and other structural analogues, the regulatory protein
XylR, of the family of transcriptional regulators which act in concert with the σ54 factor …