mTor as a potential target for the prevention and treatment of hepatocellular carcinoma
L Elisa Buitrago-Molina, A Vogel - Current Cancer Drug Targets, 2012 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a global health problem and responsible for up to
500.000 deaths annually. It usually occurs secondary to infections with hepatitis B or C …
500.000 deaths annually. It usually occurs secondary to infections with hepatitis B or C …
mTOR in viral hepatitis and hepatocellular carcinoma: function and treatment
Z Wang, W Jin, H Jin, X Wang - BioMed research international, 2014 - Wiley Online Library
As the fifth most common cancer in men and the eighth most common cancer in women,
hepatocellular carcinoma (HCC) is the leading cause of cancer‐related deaths worldwide …
hepatocellular carcinoma (HCC) is the leading cause of cancer‐related deaths worldwide …
[HTML][HTML] Activation of mTOR signaling pathway in hepatocellular carcinoma
G Ferrín, M Guerrero, V Amado… - International Journal of …, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer and occurs mainly
in patients with liver cirrhosis. The mammalian target of rapamycin (mTOR) signaling …
in patients with liver cirrhosis. The mammalian target of rapamycin (mTOR) signaling …
[HTML][HTML] Targeting the mTOR pathway in hepatocellular carcinoma: current state and future trends
MS Matter, T Decaens, JB Andersen… - Journal of …, 2014 - Elsevier
Mechanistic target of rapamycin (mTOR) regulates cell growth, metabolism and aging in
response to nutrients, cellular energy stage and growth factors. mTOR is frequently up …
response to nutrients, cellular energy stage and growth factors. mTOR is frequently up …
[PDF][PDF] The mTOR pathway in hepatic malignancies
The mechanistic/mammalian target of rapamycin (mTOR) pathway plays a critical role in
cellular metabolism, growth, and proliferation and has been evaluated as a target for therapy …
cellular metabolism, growth, and proliferation and has been evaluated as a target for therapy …
mTOR inhibitor for the treatment of hepatocellular carcinoma
M Kudo - Digestive Diseases, 2011 - karger.com
Mammalian target of rapamycin (mTOR) plays a central role in the regulation of cellular
growth, proliferation, and survival via a cytoplasmic serine/threonine kinase. mTOR also …
growth, proliferation, and survival via a cytoplasmic serine/threonine kinase. mTOR also …
[HTML][HTML] Mammalian target of rapamycin inhibition in hepatocellular carcinoma
RE Ashworth, J Wu - World journal of hepatology, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide. It is associated with a poor prognosis and has limited treatment options …
worldwide. It is associated with a poor prognosis and has limited treatment options …
mTOR inhibitors for hepatocellular cancer: a forward-moving target
G Treiber - Expert review of anticancer therapy, 2009 - Taylor & Francis
mTOR is a central regulator of cell growth and angiogenesis. The mTOR pathway is
activated in 40–50% of patients with hepatocellular cancer (HCC). In different models (ie …
activated in 40–50% of patients with hepatocellular cancer (HCC). In different models (ie …
Translational regulation in hepatocellular carcinogenesis
S Bracic Tomazic, C Schatz… - … Design, Development and …, 2021 - Taylor & Francis
The mortality of hepatocellular carcinoma (HCC) is distributed unevenly worldwide. One of
the major causes is hepatitis B or hepatitis C virus infection and the development and …
the major causes is hepatitis B or hepatitis C virus infection and the development and …
The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma
F Ponziani, V Ojetti, A Tortora… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Hepatocellular carcinoma (HCC) is a major health problem worldwide. Several
molecular pathways involved in HCC growth and progression have recently been identified …
molecular pathways involved in HCC growth and progression have recently been identified …