Expression analysis of a bovine β-casein/human lactoferrin hybrid gene in transgenic mice

SJ Kim, KW Lee, DY Yu, YM HAN, CS LEE… - … of Reproduction and …, 1997 - jstage.jst.go.jp
In our previous study, using a bovine β-casein/human lactoferrin hybrid gene, transgenic
mice were generated to target the expression of human lactoferrin (hLF) into the mammary …

High-level expression of human lactoferrin in milk of transgenic mice using genomic lactoferrin sequence

SJ Kim, BH Sohn, S Jeone, KW Pak, JS Park… - The journal of …, 1999 - jstage.jst.go.jp
In our previous study, transgenic mice were generated that expressed human lactoferrin
(hLF) in milk using cDNA under control of the 2kb bovine ƒÀ-casein promoter. The …

Expression of human lactoferrin in milk of transgenic mice

GJ Platenburg, EPA Kootwijk, PM Kooiman… - Transgenic …, 1994 - Springer
The expression of human lactoferrin (hLF) in the milk of transgenic mice is described.
Regulatory sequences derived from the bovine αS1-casein gene were fused to the coding …

[HTML][HTML] Expression of human lactoferrin in milk of transgenic mice using bovine β-casein/human lactoferrin cDNA fusion gene

SJ Kim, YY Cho, KW Lee, DY Yu, CS Lee, YM Han… - Molecules and …, 1994 - Elsevier
Transgenic mice were developed which expressed human lactoferrin (hLF) in the mammary
gland. This was achieved by using regulatory elements of bovine β-casein gene, rabbit β …

Expression of human lactoferrin in milk of transgenic animals.

R Strijker, G Platenburg, J Nuyens, F Pieper… - 1992 - cabidigitallibrary.org
Transgenic mice were generated containing constructs that comprised large flanking
regions of the bovine αs1-casein gene, its untranslated regions and signal sequence, and …

[PDF][PDF] Heterologous introns enhanced expression of human lactoferrin cDNA in mouse mammary epithelial cells

SJ Kim, DY Yu, KW Lee, YY Cho, CS Lee, YM Han… - BMB …, 1995 - researchgate.net
The expression of a recombinant human lactoferrin is reported in mouse HC11 mammary
epithelial cells. Expression of human lactoferrin (hl. F) was achieved by placing its cDNA …

Hybrid expression cassettes consisting of a milk protein promoter and a cytomegalovirus enhancer significantly increase mammary‐specific expression of human …

Y Cheng, L An, YG Yuan, Y Wang… - Molecular …, 2012 - Wiley Online Library
It is very important to develop an effective, specific, and robust expression cassette that
ensures a high level of expression in the mammary glands. In this study, we designed and …

The production of human lactoferrin in the milk of transgenic animals.

P Krimpenfort - 1993 - cabidigitallibrary.org
This review examines the expression of heterologous proteins in the milk of transgenic
animals. The expression of human lactoferrin in a mammary gland-specific expression …

The goat β‑casein/CMV chimeric promoter drives the expression of hLF in transgenic goats produced by cell transgene microinjection

T Zhang, Y Yuan, R Lu, S Xu… - International …, 2019 - spandidos-publications.com
There is growing interest in the application of lactoferrin (LF) as a drug or food additive for
animals and humans. The objective of this study was to produce transgenic cloned goats …

Variants and biotechnological use of the bovine lactoferrin-encoding gene

HM Seyfert, U Klußmann, UM Steinhoff… - … and Biological Functions, 1997 - Springer
Owing to its outstanding high and avid Fe 3+ ion-binding capacity, the secreted 80-kDa
glycoprotein lactoferrin (Lf) is thought to act as an antimicrobial agent against a broad …