Perforin-2 (P-2) is an antimicrobial protein with unique properties to kill intracellular bacteria.
Gamma delta (GD) T cells, as the major T cell population in epithelial tissues, play a central …

Atopic dermatitis (AD) is a chronic inflammatory skin disease predominantly mediated by T
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …

Atopic dermatitis (AD) is a chronic and inflammatory skin disease with intense pruritus and
xerosis. AD pathogenesis is multifactorial, involving genetic, environmental, and …

Abstract Staphylococcal enterotoxin C2 (SEC2), a superantigen, causes rapid clonal
expansion of lymphocytes and secretion of T cell growth factors, leading to a severe …

Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease that affects up to
25% of children and 10% of adults. Approximately 90% of patients with AD are colonised by …

Background Atopic dermatitis (AD) is one of the most common chronic inflammatory skin
diseases. The skin of patients with AD presents as a disbalance of the microbiome with a …

The dysregulation of skin microflora in patients with atopic dermatitis (AD) has become a
research hotspot in recent years. Metagenomic studies have shown that microbial diversity …

BACKGROUND: Atopic dermatitis (AD) is characterized by skin infiltration with eosinophils
and lymphocytes and expression of Th2 cytokines in acute skin lesions. The skin of patients …

Background Atopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis
of AD involves skin barrier defects and dysregulation of innate and adaptive immunity. Some …

While investigating the virulence traits of Staphylococcus aureus adhering to the skin of
atopic-dermatitis (AD) patients, we identified a novel open reading frame (ORF) with …