Oocyte maturation is a complex and dynamic process regulated by the coordination of
ovarian cells and numerous extraovarian signals. From mammal studies, it is learnt that lipid …

It has been found that the quality of oocytes from obese women has been compromised and
subsequent embryos displayed arrested development. The compromised quality may be …

Cholesterol is an important substrate for the synthesis of ovarian sex hormones and has an
important influence on follicular development. The cholesterol in follicular fluid is mainly …

Cholesterol is an essential component of animal cells. Different regulatory mechanisms
converge to maintain adequate levels of this lipid because both its deficiency and excess …

Oocyte intracellular lipids are mainly stored in lipid droplets (LD) providing energy for proper
growth and development. Lipids are also important signalling molecules involved in the …

The relationship among maternal lipid metabolism, fetal development, and adult disease of
the offspring represents an emerging topic of high epidemiological relevance. The present …

Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities …

Ovarian follicle provides a favorable environment for enclosed oocytes, which acquire their
competence in supporting embryo development in tight communications with somatic …

Obesity is associated with decreased pregnancy rates due, in part, to compromised oocyte
quality. The aim of the present cross-sectional study of 84 women undergoing oocyte …

Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …