Purpose This research proposed to study the changes in lipid composition in cumulus cells
(CCs) from women who achieved pregnancy compared with women who did not, after in …

Objective: To determine whether obesity alters genes important in cellular growth and
inflammation in human cumulus granulosa cells (GCs). Methods: Eight reproductive-aged …

In order to investigate the metabolic characteristics of human follicular fluid (FF) and to
reveal potential metabolic predictors of follicular development (FD) with clinical implications …

Oocytes that undergo in vitro maturation (IVM) are metabolically abnormal and accumulate
excess lipid content. However, the mechanism of lipid accumulation and the role of cumulus …

Mobilization of fatty acids from adipose tissue during metabolic stress increases the amount
of free fatty acids in blood and follicular fluid and is associated with impaired female fertility …

BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …

Background Oleic acid is an abundant free fatty acid present in livestock that are in a
negative energy-balance state, and it may have detrimental effects on female reproduction …

Lipid droplets (LDs) consist of a core of neutral lipids such as triacylglycerols and cholesteryl
esters covered by a phospholipid monolayer. Recent studies have shown that LDs not only …

Follicular fluid (FF) constitutes the microenvironment of the developing oocyte. We recently
characterized its lipid composition and found lipid signatures of positive pregnancy outcome …

Establishing an ideal human follicle culture system for oncofertility patients relies mainly on
animal models since donor tissue is scarce and often of suboptimal quality. The in vitro …