Recent clinical data demonstrate that angiotensin converting enzyme (ACE) inhibitors
possess promising antihypertensive properties. We now report on the ACE inhibitory activity …

N[N [(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-N (indan-2 yl) glycine hydrochloride
(CV-3317) and its de-esterified products, CV-3317 COOH and CV-3317-(5-OH)-COOH …

The antihypertensive action of N-[N-[(S)-1-ethoxycarbonyl-3-phenyl propyl]-L-alanyl]-N-
(indan-2-yl) glycine hydrochloride (CV-3317), a nonsulfhydryl compound characterized as …

ABSTRACT LAFFAN, ROBERT J., MORTON E. GOLDBERG, JOHN P. HIGH, THOMAS R.
SCHAEF-FER, MARGARET H. WAUGH AND BERNARD RUBIN: Antthypertensive activity in …

The antihypertensive activity of a new angiotensin converting enzyme (ACE) inhibitor, CV-
5975,(R)-3-[(S)-1-carboxy-5-(4-piperidyl) pentyl] amino-4 oxo-2, 3, 4, 5-tetrahydro-1, 5 …

Summary SCH 31846, 1-(N-[1 (5)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl)-cis, syn-
octahydro-(H-indole-2-S)-carboxylic acid; CI-907; PD 109, 763–2, is a new non-sulfhydryl …

The effects of an orally active inhibitor of angiotensin-converting enzyme (SA-446) on
systemic arterial pressure, renal function and renin release were examined in anesthetized …

CI-906 and CI-907, new orally active nonsulfhydryl angiotensin-converting enzyme
inhibitors, were examined for antihypertensive effects in unanesthetized hypertensive rats …

Hypotensive effects of SA446, an angiotensin converting enzyme (ACE) inhibitor, and effects
on the renin-angiotensin system were evaluated in conscious normotensive and 2-kidney, 1 …

The long-term oral administration of TA-6366 (5 mg/kg/day) from 4 weeks old impeded the
genetic hypertension development with only a slight decrease in heart rate in spontaneously …