Osteoarthritis (OA) is the most common joint disease and involves progressive degeneration
of articular cartilage. The aim of this study was to investigate if chondrocytes from human …

Objective The development of chondrocytic cell lines has enabled the investigation of the
role of cellular phenotype and mechanisms in articular cartilage biology and …

The distribution, expression, and functionality of gap junctions was examined in bovine
chondrocytes (BCs) isolated from mature articular cartilage. BC cells displayed …

Objective This study investigated whether chondrocytes within the cartilage matrix have the
capacity to communicate through intercellular connections mediated by voltage-gated gap …

We have previously reported that articular chondrocytes in tissue contain long cytoplasmic
arms that physically connect two distant cells. Cell-to-cell communication occurs through …

Connexons form the basis of hemichannels and gap junctions. They are composed of six
tetraspan proteins called connexins. Connexons can function as individual hemichannels …

Cell‐to‐cell interactions and gap junctions‐dependent communication are crucially involved
in chondrogenic differentiation, whereas in adult articular cartilage direct intercellular …

Cell‐to‐cell interactions and gap junctions‐dependent communication are crucially involved
in chondrogenic differentiation, while in adult articular cartilage direct intercellular …

Background information. The gap junction protein, Cx43 (connexin 43), has been implicated
in the aetiology of osteoarthritis. Studies have revealed that the size and number of gap …

Chondrocytes in cartilage and bone cells population express connexin43 (Cx43) and gap
junction intercellular communication (GJIC) is essential to synchronize cells for coordinated …