Therapeutic advances in anaplastic thyroid cancer: a current perspective

S Saini, K Tulla, AV Maker, KD Burman, BS Prabhakar - Molecular cancer, 2018 - Springer
Thyroid cancer incidence is increasing at an alarming rate, almost tripling every decade. In
2017, it was the fifth most common cancer in women. Although the majority of thyroid tumors …

Personalized therapy in patients with anaplastic thyroid cancer: targeting genetic and epigenetic alterations

N Smith, C Nucera - The Journal of Clinical Endocrinology & …, 2015 - academic.oup.com
Context: Anaplastic thyroid cancer (ATC) is the most lethal of all thyroid cancers and one of
the most aggressive human carcinomas. In the search for effective treatment options …

Advances in the management of anaplastic thyroid carcinoma: transforming a life-threatening condition into a potentially treatable disease

I Califano, A Smulever, F Jerkovich, F Pitoia - Reviews in Endocrine and …, 2024 - Springer
Anaplastic thyroid cancer (ATC) is an infrequent thyroid tumor that usually occurs in elderly
patients. There is often a history of previous differentiated thyroid cancer suggesting a …

Recent advances in the management of anaplastic thyroid cancer

S De Leo, M Trevisan, L Fugazzola - Thyroid research, 2020 - Springer
Anaplastic thyroid cancer (ATC) is undoubtedly the thyroid cancer histotype with the poorest
prognosis. The conventional treatment includes surgery, radiotherapy, and conventional …

Anaplastic thyroid carcinoma: treatment in the age of molecular targeted therapy

ME Cabanillas, M Zafereo, GB Gunn… - Journal of oncology …, 2016 - ascopubs.org
Anaplastic thyroid carcinoma is one of the most aggressive and deadly cancers in humans
and accounts for one to two cases per million persons annually. The rarity of this malignancy …

[HTML][HTML] Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies

RC Smallridge, LA Marlow… - Endocrine-related …, 2009 - erc.bioscientifica.com
Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …

[HTML][HTML] Anaplastic thyroid carcinoma: a comprehensive review of current and future therapeutic options

F Perri, G Di Lorenzo, GDV Scarpati… - World journal of clinical …, 2011 - ncbi.nlm.nih.gov
Anaplastic thyroid carcinoma (ATC) is the rarest, but deadliest histologic type among thyroid
malignancies, with a dismal median survival of 3-9 mo. Even though ATC accounts for less …

Real-world experience with targeted therapy for the treatment of anaplastic thyroid carcinoma

PC Iyer, R Dadu, R Ferrarotto, NL Busaidy, MA Habra… - Thyroid, 2018 - liebertpub.com
Background: Patients with anaplastic thyroid cancer (ATC) have a dismal prognosis, despite
systemic cytotoxic chemotherapy. The objective of this study was to investigate the efficacy …

Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies

E Molinaro, C Romei, A Biagini, E Sabini… - Nature Reviews …, 2017 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

[HTML][HTML] Novel treatments for anaplastic thyroid carcinoma

SM Ferrari, G Elia, F Ragusa, I Ruffilli, C La Motta… - Gland …, 2020 - ncbi.nlm.nih.gov
Anaplastic thyroid cancer (ATC) is one of the deadliest human cancers and it is less than 2%
of thyroid carcinomas (TCs). The standard treatment of ATC includes surgical debulking …