Pulmonary surfactant protein D inhibits lipopolysaccharide (LPS)-induced inflammatory cell responses by altering LPS binding to its receptors

M Yamazoe, C Nishitani, M Takahashi, T Katoh… - Journal of Biological …, 2008 - ASBMB
Pulmonary surfactant protein D (SP-D) is a member of the collectin family that plays an
important role in regulating innate immunity of the lung. We examined the mechanisms by …

Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism …

M Ohya, C Nishitani, H Sano, C Yamada… - Biochemistry, 2006 - ACS Publications
Pulmonary surfactant protein D (SP-D), a member of the collectin group of innate immune
proteins, plays important roles in lipopolysaccharide (LPS) recognition. We have previously …

Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain

X Nie, C Nishitani, M Yamazoe, S Ariki… - Biochemistry, 2008 - ACS Publications
Pulmonary surfactant protein D (SP-D) is a member of the collectin family and plays crucial
roles in the innate immunity of the lung. We have previously shown that surfactant protein A …

Pulmonary surfactant protein A modulates the cellular response to smooth and rough lipopolysaccharides by interaction with CD14

H Sano, H Sohma, T Muta, S Nomura… - The Journal of …, 1999 - journals.aai.org
Pulmonary surfactant protein A (SP-A) plays an important part in Ab-independent host
defense mechanisms of the lung. In this study we investigated how SP-A interacts with …

Surfactant protein D-mediated decrease of allergen-induced inflammation is dependent upon CTLA4

KW Lin, KY Jen, CJ Suarez, EC Crouch… - The Journal of …, 2010 - journals.aai.org
Pulmonary surfactant protein D (SP-D), a member of the collectin family, is an innate
immune molecule critical for defense that can also modulate adaptive immune responses …

Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway

JF Alcorn, JR Wright - American Journal of Physiology-Lung …, 2004 - journals.physiology.org
The lung collectin surfactant protein A (SP-A) has both anti-inflammatory and prophagocytic
activities. We and others previously showed that SP-A inhibits the macrophage production of …

Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4

L Guillot, V Balloy, FX McCormack… - The Journal of …, 2002 - journals.aai.org
The collectin surfactant protein-A (SP-A) is involved in the innate host defense and the
regulation of inflammatory processes in the lung. In this work we investigated the molecular …

Surfactant proteins A and D bind CD14 by different mechanisms

H Sano, H Chiba, D Iwaki, H Sohma, DR Voelker… - Journal of Biological …, 2000 - ASBMB
Surfactant proteins A (SP-A) and D (SP-D) are lung collectins that are constituents of the
innate immune system of the lung. Recent evidence (Sano, H., Sohma, H., Muta, T., Nomura …

Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding …

C Stamme, M Muller, L Hamann… - American journal of …, 2002 - atsjournals.org
Pulmonary surfactant protein (SP)-A, an innate immune molecule, modifies
lipopolysaccharide (LPS)-induced cell responses. Because SP-A avidly binds to the deep …

Surfactant protein-D and pulmonary host defense

EC Crouch - Respiratory research, 2000 - Springer
Abstract Surfactant protein-D (SP-D) participates in the innate response to inhaled
microorganisms and organic antigens, and contributes to immune and inflammatory …