Neurological disease frequently complicates HIV-1 infection. In addition to opportunistic
infections, a syndrome of combined cognitive and motor impairment, referred to as the AIDS …

Human immunodeficiency virus (HIV) infects the nervous system in the majority of patients,
causing a variety of neurological syndromes throughout the course of the disease. This …

Infection with human immunodeficiency virus type 1 (HIV-1) is frequently complicated in its
late stages by the AIDS dementia complex, a neurological syndrome characterized by …

Like most lentiviruses, HIV-1 causes both immune suppression and neurological disease.
Neurological disease may occur at any stage of HIV infection but is most apparent with …

▪ Abstract Mounting evidence suggests that cognitive dysfunction developing as a result of
HIV-1 infection is mediated at least in part by generation of excitotoxins and free radicals in …

The pathobiology of dementia that accompanies infection with the human immunodeficiency
virus involves complex interactions of the virus with the host. The virus enters the brain either …

The pathological hallmark of HIV infection in brain is productive viral replication in cells of
mononuclear phagocyte lineage including brain macrophages, microglia and …

Human immunodeficiency virus type 1 (HIV‐1) infection of the central nervous system is
associated with characteristic virological, clinical, and neuropathological findings in adults …

The neuropathogenesis of HIV-1 infection of the central nervous system (CNS) has been
intensively studied, yet it remains incompletely understood. The virus enters the CNS early …

Publisher Summary This chapter discusses various aspects of the central nervous system
complications directly associated with HIV-1—in particular, that of HIV dementia (HIVD) also …